Gene · 7004
TEAD4: TEA domain transcription factor 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TEAD4: TEA domain transcription factor 4. Genes, record 7004. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7004
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q15561 | Transcriptional enhancer factor TEF-3 | 434 | 23 | Ensembl, GeneID, HGNC |
Source UniProt
Patents25
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026017877 A1 | 2026-01-22 | 42 | Q15561 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15744 | Q15561 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15744 | Q15561 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15744 | Q15561 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15583 | Q15561 | Espacenet |
| US 11925651 B2 | 2024-03-12 | 4 | Q15561 | Espacenet |
| JP 2023553866 A | 2023-12-26 | 4 | Q15561 | Espacenet |
| US 11760728 B2 | 2023-09-19 | 4 | Q15561 | Espacenet |
| KR 1020230131189 A | 2023-09-12 | 4 | Q15561 | Espacenet |
| JP 2022147356 A | 2022-10-06 | 293 | Q15561 | Espacenet |
1 to 10 of 25
See all 25 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,396
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TEAD4 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 15 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 13 | 2025 |
| R01HD062546 | GATA Factor Function in Trophoblast | 7 | 2025 |
| R01EY015708 | Control of Cell Number in Developing Retina | 6 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 5 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 4 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 4 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 4 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 4 | 2025 |
1 to 10 of 1,396Source NIH's project files
See all 1,396 nih grantsPapers1,824
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Transcriptional Heterogeneity Underlying Cancer Cell Migration Converges on Shared Regulatory Programs. | Genes (Basel) | 2026 | 42792937 | PubTator, text mining | PubMed |
| Dysregulation of SCARB1 Alternative Splicing Disturbs Amino Acid Metabolism in Anembryonic Pregnancy. | Reprod Sci | 2026 | 42778874 | PubTator, text mining | PubMed |
| A chemoresistance-associated proliferation gene signature identified by single-cell and machine learning analysis predicts prognosis in high-grade serous ovarian carcinoma. | Transl Oncol | 2026 | 42696959 | PubTator, text mining | PubMed |
| YAP-mediated mechanotransduction promotes hepatocellular carcinoma progression by targeting ATP1A1/CXCL1 axis. | Acta Pharmacol Sin | 2026 | 42680799 | PubTator, text mining | PubMed |
| Bisphenol A promotes colorectal cancer malignancy through CXCL8 upregulation associated with p38 MAPK activation: A potential link to type 2 diabetes mellitus comorbidity. | Chem Biol Interact | 2026 | 42660439 | PubTator, text mining | PubMed |
| Marine-Derived Fungal Metabolite MHO7 Promotes Breast Cancer Apoptosis as a Hippo Pathway Regulator by Modulating the YAP-TEAD Axis. | Mar Drugs | 2026 | 42646473 | PubTator, text mining | PubMed |
| Single-cell analysis identifies a VIM+ glioma stem-like vascular-immune state linked to myeloid OSM signaling and CEBPD activity. | Front Immunol | 2026 | 42643588 | PubTator, text mining | PubMed |
| Senescent cell networks link matrix remodeling and vascular dysfunction in human fibroids. | bioRxiv | 2026 | 42620194 | PubTator, text mining | PubMed |
| KRAS Mutations Reprogram RNA m6A Modifications to Drive CD73-Dependent Immune Evasion in Colorectal Cancer. | Cancer Res | 2026 | 42525957 | PubTator, text mining | PubMed |
| EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple-Negative Breast Cancer Progression. | Adv Sci (Weinh) | 2026 | 42496060 | PubTator, text mining | PubMed |
1 to 10 of 1,824
See all 1,824 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7004
GET https://conductscience.org/api/genes/v1/7004/patents?page=2