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Gene · 7006

TEC: tec protein tyrosine kinase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TEC: tec protein tyrosine kinase. Genes, record 7006. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7006

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Gene

Symbol
TEC
HGNC
Name
tec protein tyrosine kinase
HGNC
NCBI Gene ID
7006
NCBI Gene
HGNC ID
HGNC:11719
HGNC
Ensembl
ENSG00000135605
NCBI Gene
Aliases
PSCTK4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P42680Tyrosine-protein kinase Tec6311Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1466682P42680Espacenet
EP 4641201 A22025-10-2910794P42680Espacenet
JP 2025517969 A2025-06-1210794P42680Espacenet
JP 2025032204 A2025-03-1137051P42680Espacenet
EP 4461818 A22024-11-1337051P42680Espacenet
JP 2023058610 A2023-04-2537051P42680Espacenet
US 11446398 B22022-09-2087488P42680Espacenet
US 11351168 B12022-06-072P42680Espacenet
JP 2022524081 A2022-04-27190459P42680Espacenet
US 11078247 B22021-08-0311437P42680Espacenet

1 to 10 of 47

See all 47 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
RITLECITINIBCHEMBL4085457TEC family kinase inhibitorINHIBITORChEMBL
RITLECITINIB TOSYLATECHEMBL5314649TEC family kinase inhibitorINHIBITORChEMBL

Trials24

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07228390RITLECITINIBPHASE2ClinicalTrials.gov
NCT07226531RITLECITINIBClinicalTrials.gov
NCT07200128RITLECITINIBClinicalTrials.gov
NCT07152626RITLECITINIBPHASE2ClinicalTrials.gov
NCT07152119RITLECITINIB TOSYLATEClinicalTrials.gov
NCT07029828RITLECITINIBPHASE3ClinicalTrials.gov
NCT07029711RITLECITINIBPHASE3ClinicalTrials.gov
NCT06873945RITLECITINIBPHASE3ClinicalTrials.gov
NCT06573593RITLECITINIBClinicalTrials.gov
NCT06531109RITLECITINIBClinicalTrials.gov

1 to 10 of 24

See all 24 trials

NIH grants949

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTEC papersNewest fiscal year
R01AI043957Structural Studies of a T cell Specific Tyrosine Kinase232025
P30CA008748Cancer Center Support Grant112025
P30CA016058Cancer Center Support Grant102025
P30CA016672Cancer Center Support Grant92025
P30CA021765Cancer Center Support Grant (CCSG)92025
P01AI091580Defining the Unique Properties of the Distinct Signaling Machinery Used by the TCR72025
P30CA016086Cancer Center Support Grant62025
R35GM119437Dynamics of Ligand Binding and Protein Kinase Regulation52025
ZIAAR041159Cytokine Signaling, Immunoregulation and Autoimmune and Immunodeficiency Diseases52025
R01CA177292Targeted Therapies for Lymphoid Malignancies42025

1 to 10 of 949Source NIH's project files

See all 949 nih grants

Papers1,477

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Engineered multicolor "Fluorescent Lantern" TEC-Fusion protein with tunable spectra enables multiplexed fluorescent labeling and biological imaging.Spectrochim Acta A Mol Biomol Spectrosc202742632270PubTator, text miningPubMed
JAK Inhibitors for Alopecia Areata: Approved Therapies, Efficacy, and Unanswered Questions.Drug Des Devel Ther202642824469PubTator, text miningPubMed
Patterns of Clinical Response in Rollover Adolescent Patients with Alopecia Areata Treated with Ritlecitinib in the Ongoing Long-Term, Open-Label, Phase 3 ALLEGRO-LT Study.Dermatol Ther (Heidelb)202642823604PubTator, text miningPubMed
Mechanism and Individualized Management of Hypertension Associated With Bruton Tyrosine Kinase Inhibitors: The PCSK9/Notch3 Signaling Pathway.Front Biosci (Landmark Ed)202642811994PubTator, text miningPubMed
Success of Deuruxolitinib (Leqselvi™) in Extensively Treatment-Resistant Alopecia Universalis: A Case Report.Cureus202642529366PubTator, text miningPubMed
Bruton Tyrosine Kinase as Therapeutic Target in Cardiovascular Diseases-Executive Summary.Thromb Haemost202642419695PubTator, text miningPubMed
Tectorigenin Protects Irradiation-Induced Injury of HUVECs by Inhibiting Mitophagy Through PINK1/Parkin Pathway.Front Biosci (Landmark Ed)202642216527PubTator, text miningPubMed
Targeting the BMX in cancer: molecular mechanisms and emerging therapeutic strategies.J Enzyme Inhib Med Chem202642212521PubTator, text miningPubMed
Site-Specific Phosphoproteomic Profiling of CAV1 Reveals Co-Regulatory Kinase Networks in Cancer Signaling.Int J Mol Sci202642196307PubTator, text miningPubMed
Description of the Tranquillo Phase 3 Clinical Trial Designs/Study Protocols to Assess Ritlecitinib in Adults and Adolescents with Nonsegmental Vitiligo.Dermatol Ther (Heidelb)202642171987PubTator, text miningPubMed

1 to 10 of 1,477

See all 1,477 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7006

GET https://conductscience.org/api/genes/v1/7006/patents?page=2