Gene · 701
BUB1B: BUB1 mitotic checkpoint serine/threonine kinase B
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. BUB1B: BUB1 mitotic checkpoint serine/threonine kinase B. Genes, record 701. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/701
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O60566 | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta | 1,050 | 9 | Ensembl, GeneID, HGNC |
Source UniProt
Patents18
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4641202 A2 | 2025-10-29 | 4691 | O60566 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 10043 | O60566 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 25278 | O60566 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4691 | O60566 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 25278 | O60566 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 5198 | O60566 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 25278 | O60566 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 10043 | O60566 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 113014 | O60566 | Espacenet |
| JP 2020508652 A | 2020-03-26 | 25278 | O60566 | Espacenet |
1 to 10 of 18
See all 18 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,853
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | BUB1B papers | Newest fiscal year |
|---|---|---|---|
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 24 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 18 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 14 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| R01GM074215 | Kinetochore Specification and Function | 9 | 2025 |
| P30CA014520 | UW Comprehensive Cancer Center Support | 8 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 8 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 8 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 7 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 7 | 2025 |
1 to 10 of 1,853Source NIH's project files
See all 1,853 nih grantsPapers3,969
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Immune cell enrichment characteristics and related key genes in intrauterine adhesion: insights from RNA-sequencing analysis. | Syst Biol Reprod Med | 2026 | 42763899 | PubTator, text mining | PubMed |
| BUB1B Mitotic Kinase Dependency Reveals CENP-E Inhibition as a Tractable Approach for Castration and Enzalutamide Resistant Prostate Cancer. | Cancer Res | 2026 | 42757823 | PubTator, text mining | PubMed |
| Identification of functional genes and immune cell infiltration analysis in liposarcoma. | PLoS One | 2026 | 42726806 | PubTator, text mining | PubMed |
| MYBL2 promotes malignant phenotypes and M2-like macrophage polarization through CCL2 in non-small cell lung cancer. | Mol Cell Biochem | 2026 | 42720907 | PubTator, text mining | PubMed |
| An Integrated Proteomics and Genomics Approach to Identify Essential Protein Kinases During Human Trophoblast Development. | FASEB J | 2026 | 42667124 | PubTator, text mining | PubMed |
| Comprehensive Proteomic Profiling of Alternaria gansuense Provides Insights into Candidate Virulence-Associated Proteins and Core Physiological Features. | Curr Issues Mol Biol | 2026 | 42651816 | PubTator, text mining | PubMed |
| Spindle Assembly Checkpoint Competency Determines Sensitivity to KIF18A Inhibition in Small Cell Lung Cancer. | Cancer Res Commun | 2026 | 42647139 | PubTator, text mining | PubMed |
| Spindle Assembly Checkpoint Competency Determines Sensitivity to KIF18A Inhibition in Small-Cell Lung Cancer. | bioRxiv | 2026 | 42619900 | PubTator, text mining | PubMed |
| Exploratory Preoperative Risk Stratification of Uterine Mesenchymal Tumors in Postmenopausal Women with Complementary Transcriptomic Analysis. | Diagnostics (Basel) | 2026 | 42587646 | PubTator, text mining | PubMed |
| An oxidative stress - and immunotherapy-related six-gene signature defines immune subtypes and predicts prognosis and immunotherapy response in hepatocellular carcinoma. | Gene | 2026 | 42551718 | PubTator, text mining | PubMed |
1 to 10 of 3,969
See all 3,969 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/701
GET https://conductscience.org/api/genes/v1/701/patents