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Gene · 7013

TERF1: telomeric repeat binding factor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TERF1: telomeric repeat binding factor 1. Genes, record 7013. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7013

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Gene

Symbol
TERF1
HGNC
Name
telomeric repeat binding factor 1
HGNC
NCBI Gene ID
7013
NCBI Gene
HGNC ID
HGNC:11728
HGNC
Ensembl
ENSG00000147601
NCBI Gene
Aliases
PIN2, TRBF1, TRF, TRF1, hTRF1-AS, t-TRF1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P54274Telomeric repeat-binding factor 143958Ensembl, GeneID, HGNC

Source UniProt

Patents24

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2025147176 A2025-10-0615746P54274Espacenet
JP 2025028160 A2025-02-2815746P54274Espacenet
KR 1020250010750 A2025-01-2115746P54274Espacenet
JP 2024123008 A2024-09-108629P54274Espacenet
JP 2024109657 A2024-08-1415585P54274Espacenet
US 11446398 B22022-09-2087576P54274Espacenet
JP 2022524081 A2022-04-27190547P54274Espacenet
JP 2021536249 A2021-12-2715939P54274Espacenet
JP 2021507703 A2021-02-2515899P54274Espacenet
JP 2020532987 A2020-11-1915585P54274Espacenet

1 to 10 of 24

See all 24 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,257

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTERF1 papersNewest fiscal year
R01AG016642Mechanism of the telomeric proliferation limit262025
P30CA047904Cancer Center Support Grant212025
P30CA010815Consolidated Basic Cancer Research Program172025
P30CA014195Cancer Center Support Grant (CCSG)132025
P30CA016672Cancer Center Support Grant132025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant122025
R01CA140652Role of TERRA in Telomere Maintenance and Telomere Stress Response112025
ZIACP010190Genetic Epidemiology of Telomere Maintenance and Cancer Etiology112025
P30ES025128Center for Human Health and the Environment (CHHE)92025
ZIAAG000726Function of RecQ helicases in genome stability92025

1 to 10 of 2,257Source NIH's project files

See all 2,257 nih grants

Papers3,918

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A conserved β-sheet motif mediates PIN2 hydrophilic loop-loop interactions to regulate PIN2 dynamics.Proc Natl Acad Sci U S A202642814537PubTator, text miningPubMed
A novel tRNA-derived fragment, tRF-16-WSNKP9D promotes malignant progression of colorectal carcinoma through mediating PFN1.Genomics202642805318PubTator, text miningPubMed
Comparative Analysis of Reported Gene Targets and Binding Regions of Glu-CTC tRNA Fragments Across Human Diseases.Biomolecules202642793147PubTator, text miningPubMed
Impaired telomere maintenance in rheumatoid arthritis: a case-control study of telomerase reverse transcriptase and telomeric repeat-binding factors in disease susceptibility and functional impairment.
Clin Rheumatol202642771105PubTator, text miningPubMed
Telomeres in mitosis: organization and dynamics.Nucleus202642758105PubTator, text miningPubMed
Plant halotropism: mechanisms, signaling networks, and adaptive significance.J Exp Bot202642723538PubTator, text miningPubMed
The Significance of the Regulation Between tRF-31-U5YKFN8DYDZDD and BMPER in the Pathogenesis of Gastric Cancer (GC).J Cell Mol Med202642601833PubTator, text miningPubMed
Targeting telomeres in brain vasculature does not impede initiation and progression of glioblastoma.PLoS One202642585180PubTator, text miningPubMed
CDK2-mediated phosphorylation of TRF1 S11 facilitates DNA damage repair by remodeling telomeric chromatin.Cell Death Differ202642552398PubTator, text miningPubMed
Polystyrene nanoplastics are associated with telomere-associated alterations and senescence-related changes in intestinal epithelial cells involving PPARα-POT1 regulation.Biochem Biophys Res Commun202642468176PubTator, text miningPubMed

1 to 10 of 3,918

See all 3,918 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7013

GET https://conductscience.org/api/genes/v1/7013/patents?page=2