Gene · 7013
TERF1: telomeric repeat binding factor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TERF1: telomeric repeat binding factor 1. Genes, record 7013. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7013
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P54274 | Telomeric repeat-binding factor 1 | 439 | 58 | Ensembl, GeneID, HGNC |
Source UniProt
Patents24
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025147176 A | 2025-10-06 | 15746 | P54274 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15746 | P54274 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15746 | P54274 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 8629 | P54274 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15585 | P54274 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 87576 | P54274 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 190547 | P54274 | Espacenet |
| JP 2021536249 A | 2021-12-27 | 15939 | P54274 | Espacenet |
| JP 2021507703 A | 2021-02-25 | 15899 | P54274 | Espacenet |
| JP 2020532987 A | 2020-11-19 | 15585 | P54274 | Espacenet |
1 to 10 of 24
See all 24 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,257
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TERF1 papers | Newest fiscal year |
|---|---|---|---|
| R01AG016642 | Mechanism of the telomeric proliferation limit | 26 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 21 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 17 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 13 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 13 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 12 | 2025 |
| R01CA140652 | Role of TERRA in Telomere Maintenance and Telomere Stress Response | 11 | 2025 |
| ZIACP010190 | Genetic Epidemiology of Telomere Maintenance and Cancer Etiology | 11 | 2025 |
| P30ES025128 | Center for Human Health and the Environment (CHHE) | 9 | 2025 |
| ZIAAG000726 | Function of RecQ helicases in genome stability | 9 | 2025 |
1 to 10 of 2,257Source NIH's project files
See all 2,257 nih grantsPapers3,918
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A conserved β-sheet motif mediates PIN2 hydrophilic loop-loop interactions to regulate PIN2 dynamics. | Proc Natl Acad Sci U S A | 2026 | 42814537 | PubTator, text mining | PubMed |
| A novel tRNA-derived fragment, tRF-16-WSNKP9D promotes malignant progression of colorectal carcinoma through mediating PFN1. | Genomics | 2026 | 42805318 | PubTator, text mining | PubMed |
| Comparative Analysis of Reported Gene Targets and Binding Regions of Glu-CTC tRNA Fragments Across Human Diseases. | Biomolecules | 2026 | 42793147 | PubTator, text mining | PubMed |
Impaired telomere maintenance in rheumatoid arthritis: a case-control study of telomerase reverse transcriptase and telomeric repeat-binding factors in disease susceptibility and functional impairment. | Clin Rheumatol | 2026 | 42771105 | PubTator, text mining | PubMed |
| Telomeres in mitosis: organization and dynamics. | Nucleus | 2026 | 42758105 | PubTator, text mining | PubMed |
| Plant halotropism: mechanisms, signaling networks, and adaptive significance. | J Exp Bot | 2026 | 42723538 | PubTator, text mining | PubMed |
| The Significance of the Regulation Between tRF-31-U5YKFN8DYDZDD and BMPER in the Pathogenesis of Gastric Cancer (GC). | J Cell Mol Med | 2026 | 42601833 | PubTator, text mining | PubMed |
| Targeting telomeres in brain vasculature does not impede initiation and progression of glioblastoma. | PLoS One | 2026 | 42585180 | PubTator, text mining | PubMed |
| CDK2-mediated phosphorylation of TRF1 S11 facilitates DNA damage repair by remodeling telomeric chromatin. | Cell Death Differ | 2026 | 42552398 | PubTator, text mining | PubMed |
| Polystyrene nanoplastics are associated with telomere-associated alterations and senescence-related changes in intestinal epithelial cells involving PPARα-POT1 regulation. | Biochem Biophys Res Commun | 2026 | 42468176 | PubTator, text mining | PubMed |
1 to 10 of 3,918
See all 3,918 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7013
GET https://conductscience.org/api/genes/v1/7013/patents?page=2