Gene · 7014
TERF2: telomeric repeat binding factor 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TERF2: telomeric repeat binding factor 2. Genes, record 7014. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7014
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q15554 | Telomeric repeat-binding factor 2 | 542 | 18 | Ensembl, GeneID, HGNC |
Source UniProt
Patents13
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2025147176 A | 2025-10-06 | 15747 | Q15554 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15747 | Q15554 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15747 | Q15554 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15586 | Q15554 | Espacenet |
| US 11597924 B2 | 2023-03-07 | 59 | Q15554 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 87579 | Q15554 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 190550 | Q15554 | Espacenet |
| JP 2021536249 A | 2021-12-27 | 15940 | Q15554 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 11455 | Q15554 | Espacenet |
| JP 2021507703 A | 2021-02-25 | 15900 | Q15554 | Espacenet |
1 to 10 of 13
See all 13 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,127
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TERF2 papers | Newest fiscal year |
|---|---|---|---|
| R01AG016642 | Mechanism of the telomeric proliferation limit | 41 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 23 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 15 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 15 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 14 | 2025 |
| ZIAAG000726 | Function of RecQ helicases in genome stability | 14 | 2025 |
| R01CA140652 | Role of TERRA in Telomere Maintenance and Telomere Stress Response | 13 | 2025 |
| R35CA210036 | Genome instability in cancer: telomeres and DNA repair | 13 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 12 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 9 | 2025 |
1 to 10 of 2,127Source NIH's project files
See all 2,127 nih grantsPapers3,508
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
Impaired telomere maintenance in rheumatoid arthritis: a case-control study of telomerase reverse transcriptase and telomeric repeat-binding factors in disease susceptibility and functional impairment. | Clin Rheumatol | 2026 | 42771105 | PubTator, text mining | PubMed |
| Small Molecule Modulation of TERRA RNA Quadruplex Reprograms ALT-Telomere Maintenance. | Angew Chem Int Ed Engl | 2026 | 42766372 | PubTator, text mining | PubMed |
| TRF2 couples muscle stem cell identity to regenerative repair. | Sci Adv | 2026 | 42536731 | PubTator, text mining | PubMed |
| TRF2 enriched cytoplasmic chromatin drives cGAS-STAT1-mediated inflammation in senescence. | iScience | 2026 | 42519061 | PubTator, text mining | PubMed |
| Repair and misrepair of telomeric DNA in dynamic interactions with PML nuclear bodies and lamin B1 in doxorubicin-treated cancer cells. | Nucleus | 2026 | 42489337 | PubTator, text mining | PubMed |
| Polystyrene nanoplastics are associated with telomere-associated alterations and senescence-related changes in intestinal epithelial cells involving PPARα-POT1 regulation. | Biochem Biophys Res Commun | 2026 | 42468176 | PubTator, text mining | PubMed |
| Essential Role for Telomeric Repeat-Binding Factor 2 in Cardiac Development and Function. | FASEB Bioadv | 2026 | 42405350 | PubTator, text mining | PubMed |
| Opposing Ageing-Related Transcriptomic Profiles Distinguish Opioid Exposure Liability From Dependence Liability. | Cureus | 2026 | 42339106 | PubTator, text mining | PubMed |
| Electric Field-Induced Release and Measurement Liquid Biopsy of Urinary Transcriptomics and Key Proteins from Normal and High-risk Pregnant Women. | Reprod Sci | 2026 | 42319692 | PubTator, text mining | PubMed |
| TEAD1 condensates are transcriptionally inactive storage sites on the pericentromeric heterochromatin in cancer cells. | Nat Cell Biol | 2026 | 42277434 | PubTator, text mining | PubMed |
1 to 10 of 3,508
See all 3,508 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7014
GET https://conductscience.org/api/genes/v1/7014/patents