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TFAM: transcription factor A, mitochondrial

1 protein, 51 patents, 0 drugs, 0 trials, 3,108 NIH grants and 6,394 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTFAMHGNC
Nametranscription factor A, mitochondrialHGNC
NCBI Gene ID7019NCBI Gene
HGNC IDHGNC:11741HGNC
EnsemblENSG00000108064NCBI Gene
AliasesMTDPS15, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q00059Transcription factor A, mitochondrial24616Ensembl, GeneID, HGNCUniProt

Patents 51

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19315Q00059Espacenet
JP 2026004568 A2026-01-1467408Q00059Espacenet
EP 4641201 A22025-10-2916937Q00059Espacenet
JP 2025147176 A2025-10-0613129Q00059Espacenet
JP 2025147176 A2025-10-0615751Q00059Espacenet
EP 4620519 A22025-09-2415Q00059Espacenet
EP 4620520 A22025-09-2415Q00059Espacenet
EP 4620521 A22025-09-2415Q00059Espacenet
JP 2025529142 A2025-09-047863Q00059Espacenet
US 12371689 B22025-07-297863Q00059Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3108

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30AG028740University of Florida Older Americans Independence Center (OAIC)142,025NIH's project files
P30CA016672Cancer Center Support Grant142,025NIH's project files
R01EY010804Setting the Stage for Replacement of Mitochondrial Genes122,025NIH's project files
R35GM118086Mechanistic studies of nucleic acid enzymes involved in DNA replication, transcription, and innate immunity122,025NIH's project files
R35GM128854Chemical and Molecular Mechanisms of Mitochondrial DNA Degradation112,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)92,025NIH's project files
ZIAES065078Molecular Characterization Of The Mitochondrial Dna Polymerase92,025NIH's project files
P30CA008748Cancer Center Support Grant82,025NIH's project files
P20GM103427Nebraska Research Network in Functional Genomics72,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program72,025NIH's project files

Papers 6394

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42827098PubTator, text miningPubMed
42818300PubTator, text miningPubMed
42815861PubTator, text miningPubMed
42813448PubTator, text miningPubMed
42810682PubTator, text miningPubMed
42800684PubTator, text miningPubMed
42792154PubTator, text miningPubMed
42791642PubTator, text miningPubMed
42779802PubTator, text miningPubMed
42761405PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license