Gene · 7023
TFAP4: transcription factor AP-4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TFAP4: transcription factor AP-4. Genes, record 7023. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7023
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q01664 | Transcription factor AP-4 | 338 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 222 | Q01664 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15757 | Q01664 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 222 | Q01664 | Espacenet |
| JP 2025506185 A | 2025-03-07 | 30 | Q01664 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15757 | Q01664 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15757 | Q01664 | Espacenet |
| EP 4479067 A2 | 2024-12-25 | 30 | Q01664 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15596 | Q01664 | Espacenet |
| JP 2023544161 A | 2023-10-20 | 59 | Q01664 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 89852 | Q01664 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,181
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TFAP4 papers | Newest fiscal year |
|---|---|---|---|
| ZIAHD001607 | Protein Trafficking In The Endosomal-Lysosomal System | 25 | 2025 |
| K08NS123552 | Development of a Translational Research Platform to Understand and treat Defective Protein Trafficking in Childhood-Onset Hereditary Spastic Paraplegia | 8 | 2025 |
| P50HD105351 | Boston Children's Hospital/HMS Intellectual and Developmental Disabilities Research Center | 5 | 2025 |
| R35GM119525 | Molecular mechanisms of coat assembly and regulation in membrane trafficking pathways | 5 | 2025 |
| P30AI050410 | The University of North Carolina Center for AIDS Research | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 3 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 3 | 2025 |
| P30EY008126 | Core Grant in Vision Research | 3 | 2025 |
1 to 10 of 1,181Source NIH's project files
See all 1,181 nih grantsPapers1,530
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Conserved neuronal-like and secretory programs define the spatial architecture of gastroenteropancreatic neuroendocrine tumors. | J Clin Invest | 2026 | 42678737 | PubTator, text mining | PubMed |
| Splice effect of a synonymous variant in AP4B1: multiomics approach establishes the diagnosis in two sisters with spastic paraplegia. | Hum Mutat | 2026 | 42597316 | PubTator, text mining | PubMed |
| Clinical and genetic characteristics of pediatric hereditary spastic paraplegia in the Eastern Levant. | Eur J Paediatr Neurol | 2026 | 42462372 | PubTator, text mining | PubMed |
| Potential Relationship Between YTHDF3 and CFTR in Myocardial Ischemia-Reperfusion Injury. | J Cell Mol Med | 2026 | 42265766 | PubTator, text mining | PubMed |
| GOT1 promotes endometrial cancer progression by regulating ferroptosis through the STAT3-GPX4 axis and attenuating medroxyprogesterone acetate sensitivity. | Cancer Gene Ther | 2026 | 42230821 | PubTator, text mining | PubMed |
| Carbonized Composites Containing Silica Aerogels with Enhanced Hydrophobicity and Thermal Insulation via Glass Fiber and Hollow Microsphere Reinforcement. | Gels | 2026 | 42196123 | PubTator, text mining | PubMed |
| Identification of Key Genes and Exploration of Therapeutic Targets for Chronic Tendon Injury Based on Bioinformatics and Machine Learning. | Int J Gen Med | 2026 | 42157878 | PubTator, text mining | PubMed |
| CRISPR/Cas9 loss-of-function screen in a neuronal model of AP-4 deficiency identifies ATG9A trafficking modulators. | JCI Insight | 2026 | 42154535 | PubTator, text mining | PubMed |
| Protein arginine methyltransferases in cancer: mechanisms, functions, and therapeutic opportunities. | J Biomed Sci | 2026 | 41928257 | PubTator, text mining | PubMed |
| YqeK governs the acquisition and removal of nucleoside tetraphosphate caps in Firmicutes. | Nucleic Acids Res | 2026 | 41873760 | PubTator, text mining | PubMed |
1 to 10 of 1,530
See all 1,530 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7023
GET https://conductscience.org/api/genes/v1/7023/patents?page=2