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Gene · 7025

NR2F1: nuclear receptor subfamily 2 group F member 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NR2F1: nuclear receptor subfamily 2 group F member 1. Genes, record 7025. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7025

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Gene

Symbol
NR2F1
HGNC
Name
nuclear receptor subfamily 2 group F member 1
HGNC
NCBI Gene ID
7025
NCBI Gene
HGNC ID
HGNC:7975
HGNC
Ensembl
ENSG00000175745
NCBI Gene
Aliases
BBOAS, BBSOAS, COUP-TFI, COUPTF1, EAR-3, EAR3, ERBAL3, SVP44, TCFCOUP1, TFCOUP1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P10589COUP transcription factor 14231Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19114P10589Espacenet
JP 2026004568 A2026-01-1456158P10589Espacenet
EP 4641201 A22025-10-295269P10589Espacenet
JP 2025147176 A2025-10-0615426P10589Espacenet
JP 2025517969 A2025-06-125269P10589Espacenet
JP 2025028160 A2025-02-2815426P10589Espacenet
KR 1020250010750 A2025-01-2115426P10589Espacenet
WO 2024214081 A12024-10-17114P10589Espacenet
JP 2024109657 A2024-08-1415265P10589Espacenet
US 11446398 B22022-09-2058478P10589Espacenet

1 to 10 of 32

See all 32 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,530

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNR2F1 papersNewest fiscal year
R01CA109182Functional Determinants of Metastatic Dormancy172025
P30CA196521The Tisch Cancer Institute - Cancer Center Support Grant92025
P30CA008748Cancer Center Support Grant62025
R01HG003988Functionally Assessing Transcriptional Enhancers In Vivo62025
P01CA022443Molecular Biology and Genetics of Human Tumor Viruses52025
U54MD012392RCMI Center for Health Disparities Research52025
P30DK020593Vanderbilt Diabetes Research Center42025
P50CA097186The Pacific Northwest Prostate Cancer SPORE42025
R01HL137766Molecular Mechanisms of Atrial Development and Regeneration42025
R01NS099099Genetic Studies of Cortex Structure and Development42025

1 to 10 of 1,530Source NIH's project files

See all 1,530 nih grants

Papers1,849

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
An NR2F1-dependent retinoic acid network controls retinal specialization in mice and reveals foveal hypoplasia in patients with BBSOAS.bioRxiv202642818154PubTator, text miningPubMed
Single-cell transcriptomic atlas of the human fetal uveal tract reveals heterogeneity in melanocyte populations.iScience202642765034PubTator, text miningPubMed
Repurposing of lansoprazole and nitazoxanide as NR2F2 inhibitors in the gastric cancer cell line GCIY: computational insights and siRNA-mediated in vitro tests.Front Chem202642712908PubTator, text miningPubMed
USP11-mediated deubiquitination regulates the protein stability of NR2F1.Acta Biochim Biophys Sin (Shanghai)202642671899PubTator, text miningPubMed
A de novo NR2F1 c.330 C > A variant in Bosch-Boonstra-Schaaf optic atrophy syndrome presenting with early-onset developmental and epileptic encephalopathy.Mol Biol Rep202642606787PubTator, text miningPubMed
Self-supervised representations reveal the genetic architecture of human cortical folding.bioRxiv202642538962PubTator, text miningPubMed
USP15 mutation associated with autism spectrum disorder alters progenitor fate and neuronal maturation in human brain organoids.Mol Cells202642526765PubTator, text miningPubMed
Diagnostic Yield and Clinical Impact of Comprehensive WES/WGS Testing Beyond Common Genetic Causes in Hereditary Optic Atrophy.Clin Genet202642363686PubTator, text miningPubMed
Pediatric hereditary optic neuropathies in the United Arab Emirates.Ophthalmic Genet202642299460PubTator, text miningPubMed
The NR2F1-Related 5q14.3-q21.1 deletion causing periventricular heterotopia with cerebral visual impairment: a longitudinal case report and genotype-phenotype analysis.Front Genet202642180515PubTator, text miningPubMed

1 to 10 of 1,849

See all 1,849 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7025

GET https://conductscience.org/api/genes/v1/7025/patents?page=2