Gene · 7025
NR2F1: nuclear receptor subfamily 2 group F member 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NR2F1: nuclear receptor subfamily 2 group F member 1. Genes, record 7025. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7025
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P10589 | COUP transcription factor 1 | 423 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents32
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026515744 A | 2026-05-19 | 114 | P10589 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 56158 | P10589 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 5269 | P10589 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15426 | P10589 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 5269 | P10589 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15426 | P10589 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15426 | P10589 | Espacenet |
| WO 2024214081 A1 | 2024-10-17 | 114 | P10589 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15265 | P10589 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 58478 | P10589 | Espacenet |
1 to 10 of 32
See all 32 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,530
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NR2F1 papers | Newest fiscal year |
|---|---|---|---|
| R01CA109182 | Functional Determinants of Metastatic Dormancy | 17 | 2025 |
| P30CA196521 | The Tisch Cancer Institute - Cancer Center Support Grant | 9 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| R01HG003988 | Functionally Assessing Transcriptional Enhancers In Vivo | 6 | 2025 |
| P01CA022443 | Molecular Biology and Genetics of Human Tumor Viruses | 5 | 2025 |
| U54MD012392 | RCMI Center for Health Disparities Research | 5 | 2025 |
| P30DK020593 | Vanderbilt Diabetes Research Center | 4 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 4 | 2025 |
| R01HL137766 | Molecular Mechanisms of Atrial Development and Regeneration | 4 | 2025 |
| R01NS099099 | Genetic Studies of Cortex Structure and Development | 4 | 2025 |
1 to 10 of 1,530Source NIH's project files
See all 1,530 nih grantsPapers1,849
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| An NR2F1-dependent retinoic acid network controls retinal specialization in mice and reveals foveal hypoplasia in patients with BBSOAS. | bioRxiv | 2026 | 42818154 | PubTator, text mining | PubMed |
| Single-cell transcriptomic atlas of the human fetal uveal tract reveals heterogeneity in melanocyte populations. | iScience | 2026 | 42765034 | PubTator, text mining | PubMed |
| Repurposing of lansoprazole and nitazoxanide as NR2F2 inhibitors in the gastric cancer cell line GCIY: computational insights and siRNA-mediated in vitro tests. | Front Chem | 2026 | 42712908 | PubTator, text mining | PubMed |
| USP11-mediated deubiquitination regulates the protein stability of NR2F1. | Acta Biochim Biophys Sin (Shanghai) | 2026 | 42671899 | PubTator, text mining | PubMed |
| A de novo NR2F1 c.330 C > A variant in Bosch-Boonstra-Schaaf optic atrophy syndrome presenting with early-onset developmental and epileptic encephalopathy. | Mol Biol Rep | 2026 | 42606787 | PubTator, text mining | PubMed |
| Self-supervised representations reveal the genetic architecture of human cortical folding. | bioRxiv | 2026 | 42538962 | PubTator, text mining | PubMed |
| USP15 mutation associated with autism spectrum disorder alters progenitor fate and neuronal maturation in human brain organoids. | Mol Cells | 2026 | 42526765 | PubTator, text mining | PubMed |
| Diagnostic Yield and Clinical Impact of Comprehensive WES/WGS Testing Beyond Common Genetic Causes in Hereditary Optic Atrophy. | Clin Genet | 2026 | 42363686 | PubTator, text mining | PubMed |
| Pediatric hereditary optic neuropathies in the United Arab Emirates. | Ophthalmic Genet | 2026 | 42299460 | PubTator, text mining | PubMed |
| The NR2F1-Related 5q14.3-q21.1 deletion causing periventricular heterotopia with cerebral visual impairment: a longitudinal case report and genotype-phenotype analysis. | Front Genet | 2026 | 42180515 | PubTator, text mining | PubMed |
1 to 10 of 1,849
See all 1,849 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7025
GET https://conductscience.org/api/genes/v1/7025/patents?page=2