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Gene · 7030

TFE3: transcription factor binding to IGHM enhancer 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TFE3: transcription factor binding to IGHM enhancer 3. Genes, record 7030. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7030

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Gene

Symbol
TFE3
HGNC
Name
transcription factor binding to IGHM enhancer 3
HGNC
NCBI Gene ID
7030
NCBI Gene
HGNC ID
HGNC:11752
HGNC
Ensembl
ENSG00000068323
NCBI Gene
Aliases
MRXSPF, RCCP2, RCCX1, TFEA, bHLHe33
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P19532Transcription factor E35751Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467424P19532Espacenet
EP 4650780 A22025-11-194942P19532Espacenet
JP 2025147176 A2025-10-0615765P19532Espacenet
JP 2025517970 A2025-06-124942P19532Espacenet
JP 2025028160 A2025-02-2815765P19532Espacenet
KR 1020250010750 A2025-01-2115765P19532Espacenet
JP 2024109657 A2024-08-1415604P19532Espacenet
US 11884978 B22024-01-30761P19532Espacenet
US 11860162 B22024-01-021258P19532Espacenet
US 11446398 B22022-09-2089858P19532Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,154

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTFE3 papersNewest fiscal year
P30CA008748Cancer Center Support Grant732025
ZIABC011028Clinical Studies of the Molecular Genetic Basis of Kidney Cancer272025
ZIDBC011089Clinical Nursing and Data Management Core242025
ZIABC011043Molecular Therapeutics of Kidney Cancer: MET Gene and BHD Gene232025
P30CA016672Cancer Center Support Grant222025
ZIAHL006151Lysosome biogenesis and homeostasis222025
P50CA217694SPORE in Soft Tissue Sarcoma202025
ZIABC011038Molecular Therapeutics of Kidney Cancer: VHL Gene and Fumarate Hydratase Gene202025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes112025
R01AR043369MITF from control of pigmentation to melanoma risk112025

1 to 10 of 1,154Source NIH's project files

See all 1,154 nih grants

Papers3,398

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Immunoreactivity of GPNMB (glycoprotein nonmetastatic melanoma protein B) across the spectrum of uterine mesenchymal tumours.Histopathology202642791032PubTator, text miningPubMed
mTORC1-TFEB/TFE3 signaling is associated with bile acid diversification during hepatic metabolic adaptation.Sci Adv202642789715PubTator, text miningPubMed
Fusion-driven oncogenic programs shape the immune landscape in translocation renal cell carcinoma.Nat Commun202642786155PubTator, text miningPubMed
Emerging patterns of kidney cancer in young adults: where do we stand?Crit Rev Oncol Hematol202642764100PubTator, text miningPubMed
A partial response to atezolizumab in alveolar soft part sarcoma with near-complete resolution of extensive pulmonary metastases: a case report.Front Oncol202642761021PubTator, text miningPubMed
Adult Mixed Epithelial and Stromal Tumor of the Kidney Harbors Recurrent Whole Chromosome 12 Gain.Am J Surg Pathol202642750419PubTator, text miningPubMed
Clinical Outcomes, Treatment Patterns, and Molecular Heterogeneity of TFE3-Rearranged Renal Cell Carcinoma: A Multicenter Real-World Study.Cancer Med202642726730PubTator, text miningPubMed
Case Report: Acquired CDKN2A/B deletion and mTOR inhibitor resistance in TSC2-mutant metastatic epithelioid angiomyolipoma.Front Med (Lausanne)202642712743PubTator, text miningPubMed
[Birt-Hogg-Dubé syndrome-associated renal tumors: a clinicopathological and molecular genetic analysis of ten cases].Zhonghua Bing Li Xue Za Zhi202642706109PubTator, text miningPubMed
EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy.PLoS One202642691050PubTator, text miningPubMed

1 to 10 of 3,398

See all 3,398 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7030

GET https://conductscience.org/api/genes/v1/7030/patents?page=2