Gene · 7032
TFF2: trefoil factor 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TFF2: trefoil factor 2. Genes, record 7032. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7032
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q03403 | Trefoil factor 2 | 129 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents48
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026022373 A1 | 2026-01-29 | 21 | Q03403 | Espacenet |
| EP 4684804 A1 | 2026-01-28 | 21 | Q03403 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 67925 | Q03403 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3464 | Q03403 | Espacenet |
| JP 2025158975 A | 2025-10-17 | 1 | Q03403 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 13132 | Q03403 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7865 | Q03403 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7865 | Q03403 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3464 | Q03403 | Espacenet |
| JP 2025514630 A | 2025-05-09 | 21 | Q03403 | Espacenet |
1 to 10 of 48
See all 48 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants861
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TFF2 papers | Newest fiscal year |
|---|---|---|---|
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 38 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 30 | 2025 |
| I01BX000930 | Oxyntic Atrophy and Novel Gastric Lineages. | 27 | 2025 |
| R01DK094989 | REGULATION OF ATROPHY-INDUCED PROGENITOR CELLS IN THE GASTRIC CORPUS | 24 | 2025 |
| R01DK101332 | Induction and Evolution of Metaplasia in the Stomach | 24 | 2025 |
| P30DK052574 | Host-environment interactions in the pathophysiology of digestive disease | 23 | 2025 |
| R01DK105129 | MECHANISMS OF CHIEF CELL DEDIFFERENTIATION | 23 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 19 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 11 | 2025 |
| P30DK056338 | Texas Medical Center Digestive Diseases Center | 11 | 2025 |
1 to 10 of 861Source NIH's project files
See all 861 nih grantsPapers1,620
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Autoimmune gastritis diverges from a shared corpus origin: molecular reconstruction of the adenocarcinoma axis and clinical anchoring of the neuroendocrine axis. | Front Immunol | 2026 | 42712509 | PubTator, text mining | PubMed |
| Spatial transcriptomics reveals club cell features and strong CLDN18 expression along the mucinous pathway to invasive mucinous adenocarcinoma. | J Pathol | 2026 | 42711771 | PubTator, text mining | PubMed |
| Shengjiang powder ameliorates gastric mucosal injury through activating SIRT1/FOXO1 anti-oxidative stress. | Front Pharmacol | 2026 | 42666336 | PubTator, text mining | PubMed |
| Glycolytic reprogramming in precancerous lesions of gastric cancer progression: pathogenesis and therapeutic potential. | Front Oncol | 2026 | 42657117 | PubTator, text mining | PubMed |
| Retraction Statement. | Digestion | 2026 | 42536604 | PubTator, text mining | PubMed |
| Crosstalk between TFF2+ HCC cells and regulatory T cells drives hepatocellular carcinoma prometastatic niche formation and portal vein tumor thrombosis. | Cell Signal | 2026 | 42471073 | PubTator, text mining | PubMed |
| Physical, chemical, and structural properties of human gastric organoid-derived mucus. | Am J Physiol Gastrointest Liver Physiol | 2026 | 42460667 | PubTator, text mining | PubMed |
| SRY-Box 9-Driven Spasmolytic Polypeptide-Expressing Metaplasia Cell Lineage Plasticity Is a Potential Therapeutic Target That Mitigates Risk of Metaplastic Progression to Gastric Cancer. | Gastroenterology | 2026 | 42448241 | PubTator, text mining | PubMed |
| Spasmolytic Polypeptide-Expressing Metaplasia in Chronic Atrophic Gastritis and Its Role in the Progression From Gastritis to Gastric Cancer. | J Dig Dis | 2026 | 42438264 | PubTator, text mining | PubMed |
| Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review). | Mol Med Rep | 2026 | 42429138 | PubTator, text mining | PubMed |
1 to 10 of 1,620
See all 1,620 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7032
GET https://conductscience.org/api/genes/v1/7032/patents?page=2