Gene · 7033
TFF3: trefoil factor 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TFF3: trefoil factor 3. Genes, record 7033. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7033
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q07654 | Trefoil factor 3 | 80 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents38
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2025166063 A1 | 2025-08-07 | 12 | Q07654 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 2585 | Q07654 | Espacenet |
| US 9347952 B2 | 2016-05-24 | 440 | Q07654 | Espacenet |
| WO 2015174544 A | 2015-11-19 | 45 | Q07654 | Espacenet |
| JP 2013537168 A | 2013-09-30 | 3 | Q07654 | Espacenet |
| EP 2567970 A1 | 2013-03-13 | 440 | Q07654 | Espacenet |
| WO 2011150944 A1 | 2011-12-08 | 3 | Q07654 | Espacenet |
| US 7951546 B2 | 2011-05-31 | 59 | Q07654 | Espacenet |
| US 7939268 B2 | 2011-05-10 | 59 | Q07654 | Espacenet |
| WO 2011044902 A1 | 2011-04-21 | 3 | Q07654 | Espacenet |
1 to 10 of 38
See all 38 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,598
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TFF3 papers | Newest fiscal year |
|---|---|---|---|
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 33 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 16 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 12 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 11 | 2025 |
| R01DK101332 | Induction and Evolution of Metaplasia in the Stomach | 11 | 2025 |
| I01BX000930 | Oxyntic Atrophy and Novel Gastric Lineages. | 10 | 2025 |
| R01AG034853 | Biomarker-Based Diagnostic Algorithms To Prevent, Detect And Guide Treatment Of Kidney Disease In Persons Living With HIV | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30DK034987 | Center for Gastrointestinal Biology and Disease | 6 | 2025 |
| P30DK056338 | Texas Medical Center Digestive Diseases Center | 6 | 2025 |
1 to 10 of 1,598Source NIH's project files
See all 1,598 nih grantsPapers3,041
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Diagnostic Value of Serum HE4, TFF3, and CA72-4 for Gastric Cancer Stratified by Helicobacter pylori Infection Status. | Br J Hosp Med (Lond) | 2026 | 42812095 | PubTator, text mining | PubMed |
| Serum Trefoil Factor 3 in Endometrioid Endometrial Carcinoma: Exploratory Diagnostic Value and Association with Lymphovascular Space Invasion. | J Clin Med | 2026 | 42739604 | PubTator, text mining | PubMed |
| Adhesion-Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin-Responsive IBD Therapy. | Adv Sci (Weinh) | 2026 | 42725754 | PubTator, text mining | PubMed |
| Longitudinal assessment of glomerular and tubular kidney function after COVID-19: a prospective cohort study. | Scand J Clin Lab Invest | 2026 | 42690026 | PubTator, text mining | PubMed |
| Decoding chromosomal instability in neutrophil signature in the pathogenesis of periodontitis: evidence from artificial intelligence-driven multi-omics and in vitro validation. | Cytotechnology | 2026 | 42670405 | PubTator, text mining | PubMed |
| Diagnostic Accuracy of a Capsule Sponge Trefoil Factor 3 Test for Barrett's Esophagus in Patients With Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis. | Am J Gastroenterol | 2026 | 42669464 | PubTator, text mining | PubMed |
| Correction: Hepatic origin of increased serum TFF3 in gastric cancer bearing subjects. | Gastric Cancer | 2026 | 42640351 | PubTator, text mining | PubMed |
| Patient-Derived Organoid and Single-Cell Multiomics Reveal Evolution Driven by CEACAM6/KRT19-Mediated Heterogeneity. | FASEB J | 2026 | 42622615 | PubTator, text mining | PubMed |
| Impact of a durable left ventricular assist device on inflammation and cardiac remodelling in subjects with advanced heart failure. | Open Heart | 2026 | 42580841 | PubTator, text mining | PubMed |
| Oxygen-enhanced assembloid-based vascularized intestinal-on-a-chip for radioprotective drug evaluation. | Front Toxicol | 2026 | 42534747 | PubTator, text mining | PubMed |
1 to 10 of 3,041
See all 3,041 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7033
GET https://conductscience.org/api/genes/v1/7033/patents?page=2