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TFRC: transferrin receptor

1 protein, 597 patents, 3 drugs, 8 trials, 11,026 NIH grants and 25,335 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTFRCHGNC
Nametransferrin receptorHGNC
NCBI Gene ID7037NCBI Gene
HGNC IDHGNC:11763HGNC
EnsemblENSG00000072274NCBI Gene
AliasesCD71, IMD46, T9, TFR, TFR1, TR, TRFR, p90NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P02786Transferrin receptor protein 176024Ensembl, GeneID, HGNCUniProt

Patents 597

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4828749 A12026-10-2823P02786Espacenet
EP 4824103 A12026-10-212P02786Espacenet
WO 2026169926 A12026-08-131P02786Espacenet
US 12662545 B22026-06-231P02786Espacenet
JP 2026519919 A2026-06-191P02786Espacenet
JP 2026095522 A2026-06-1110P02786Espacenet
WO 2026116332 A2026-06-0417P02786Espacenet
JP 2026086434 A2026-05-26228P02786Espacenet
JP 2026086568 A2026-05-26150P02786Espacenet
JP 2026086616 A2026-05-26102P02786Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
A27.15CHEMBL2109494Transferrin receptor protein 1 antagonistANTAGONISTChEMBL
E2.3CHEMBL2109495Transferrin receptor inhibitorINHIBITORChEMBL
PABINAFUSP ALFACHEMBL4594565Transferrin receptor binding agentBINDING AGENTChEMBL

Trials 8

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05594992PABINAFUSP ALFAPHASE3ClinicalTrials.gov
NCT04573023PABINAFUSP ALFAPHASE3ClinicalTrials.gov
NCT04348136PABINAFUSP ALFAPHASE2/PHASE3ClinicalTrials.gov
NCT03708965PABINAFUSP ALFAPHASE2ClinicalTrials.gov
NCT03568175PABINAFUSP ALFAPHASE2/PHASE3ClinicalTrials.gov
NCT03359213PABINAFUSP ALFAPHASE2ClinicalTrials.gov
NCT00003082A27.15PHASE1ClinicalTrials.gov
NCT00003082E2.3PHASE1ClinicalTrials.gov

NIH grants 11026

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant842,025NIH's project files
P30CA016672Cancer Center Support Grant502,025NIH's project files
P30CA016042Cancer Center Support Grant342,025NIH's project files
P30CA006973Regional Oncology Research Center222,025NIH's project files
ZIAHD001602Regulation Of Intracellular Iron Metabolism212,025NIH's project files
ZIAHD001607Protein Trafficking In The Endosomal-Lysosomal System212,025NIH's project files
R01ES010563Mechanisms of Manganese Neurotoxicity202,025NIH's project files
P30CA016087Cancer Center Support Grant192,025NIH's project files
P30CA086862Cancer Center Support Grant192,025NIH's project files
R01DK103794Systematic Genetic Dissection of Human Erythropoiesis192,025NIH's project files

Papers 25335

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825541PubTator, text miningPubMed
42824020PubTator, text miningPubMed
42823535PubTator, text miningPubMed
42819569PubTator, text miningPubMed
42817178PubTator, text miningPubMed
42816619PubTator, text miningPubMed
42816117PubTator, text miningPubMed
42814552PubTator, text miningPubMed
42803694PubTator, text miningPubMed
42802838PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license