ConductScience.org, home

Library / Genes

TGFB3: transforming growth factor beta 3

1 protein, 273 patents, 3 drugs, 110 trials, 4,509 NIH grants and 9,642 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTGFB3HGNC
Nametransforming growth factor beta 3HGNC
NCBI Gene ID7043NCBI Gene
HGNC IDHGNC:11769HGNC
EnsemblENSG00000119699NCBI Gene
AliasesARVD, ARVD1, LDS5, RNHF, TGF-beta3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P10600Transforming growth factor beta-3 proprotein41211Ensembl, GeneID, HGNCUniProt

Patents 273

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026094314 A2026-06-0968P10600Espacenet
JP 2026086743 A2026-05-26196P10600Espacenet
JP 2026082951 A2026-05-1916P10600Espacenet
JP 2026511149 A2026-04-107256P10600Espacenet
JP 2026506884 A2026-02-2766P10600Espacenet
JP 2026021360 A2026-02-10159P10600Espacenet
EP 4683651 A22026-01-287256P10600Espacenet
WO 2026017857 A12026-01-2230P10600Espacenet
WO 2026017864 A12026-01-2230P10600Espacenet
US 12528850 B22026-01-20112P10600Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BINTRAFUSP ALFACHEMBL4298024Transforming growth factor beta binding agentBINDING AGENTChEMBL
FRESOLIMUMABCHEMBL1743022Transforming growth factor beta-3 inhibitorINHIBITORChEMBL
LUSPATERCEPTCHEMBL3039545Transforming growth factor beta inhibitorINHIBITORChEMBL

Trials 110

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07465029LUSPATERCEPTClinicalTrials.gov
NCT07463820LUSPATERCEPTPHASE2ClinicalTrials.gov
NCT07450313LUSPATERCEPTPHASE2ClinicalTrials.gov
NCT07362095LUSPATERCEPTPHASE1/PHASE2ClinicalTrials.gov
NCT07338344LUSPATERCEPTPHASE2ClinicalTrials.gov
NCT07331818LUSPATERCEPTPHASE2ClinicalTrials.gov
NCT07215975LUSPATERCEPTClinicalTrials.gov
NCT07096297LUSPATERCEPTPHASE2ClinicalTrials.gov
NCT07075406LUSPATERCEPTClinicalTrials.gov
NCT07073690LUSPATERCEPTClinicalTrials.gov

NIH grants 4509

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant212,025NIH's project files
P30CA016672Cancer Center Support Grant202,025NIH's project files
P30CA054174Mays Cancer Center at UT Health SA162,025NIH's project files
P30AR073752Washington University Rheumatic Diseases Research Resource-based Center102,025NIH's project files
P30EY008098Core Grant for Vision Research102,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award102,025NIH's project files
ZIAAI001203The Role of Transforming Growth Factor Beta (TGFbeta) in Promoting Allergic Inflammation102,025NIH's project files
P30AR074992RESOURCE BASED CENTER FOR MUSCULOSKELETAL BIOLOGY AND MEDICINE92,025NIH's project files
P30CA016058Cancer Center Support Grant92,025NIH's project files
P30EY003790Core Grant for Vision Research92,025NIH's project files

Papers 9642

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42821015PubTator, text miningPubMed
42809990PubTator, text miningPubMed
42796630PubTator, text miningPubMed
42787770PubTator, text miningPubMed
42722414PubTator, text miningPubMed
42707849PubTator, text miningPubMed
42696276PubTator, text miningPubMed
42694986PubTator, text miningPubMed
42670067PubTator, text miningPubMed
42616390PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license