Gene · 7045
TGFBI: transforming growth factor beta induced
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TGFBI: transforming growth factor beta induced. Genes, record 7045. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7045
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q15582 | Transforming growth factor-beta-induced protein ig-h3 | 683 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents156
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026515744 A | 2026-05-19 | 369 | Q15582 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 67520 | Q15582 | Espacenet |
| JP 2026000906 A | 2026-01-06 | 84 | Q15582 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 14003 | Q15582 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 16289 | Q15582 | Espacenet |
| EP 4641203 A2 | 2025-10-29 | 495 | Q15582 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 13164 | Q15582 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7873 | Q15582 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7873 | Q15582 | Espacenet |
| JP 2025517967 A | 2025-06-12 | 495 | Q15582 | Espacenet |
1 to 10 of 156
See all 156 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,003
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TGFBI papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 15 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 8 | 2025 |
| P30EY000331 | Vision Research Core at UCLA | 8 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 7 | 2025 |
| P30ES009089 | Center for Environmental Health in Northern Manhattan | 7 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 5 | 2025 |
| P50CA127001 | SPORE in Brain Cancer | 5 | 2025 |
| P50CA236733 | Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal Cancer | 5 | 2025 |
| R01AI136946 | Mechanisms and consequence of helical shape generation in Helicobacter pylori | 5 | 2025 |
| R01EY020581 | Role of Oxidative Stress in Pathogenesis of Fuchs Endothelial Corneal Dystrophy | 5 | 2025 |
1 to 10 of 2,003Source NIH's project files
See all 2,003 nih grantsPapers3,774
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Exosome-Mediated Bidirectional Signaling Regulates Glioma Stem-Cell Homeostasis and Radiation-Induced Plasticity. | bioRxiv | 2026 | 42818566 | PubTator, text mining | PubMed |
| Twist in the fibril: Structure guides inhibition of TGFBIp amyloid formation. | Proc Natl Acad Sci U S A | 2026 | 42804651 | PubTator, text mining | PubMed |
| A Novel Loss-of-Function Variant in TGFBI Associated with Non-Syndromic Orofacial Clefts in a Chinese Pedigree. | Genes (Basel) | 2026 | 42792893 | PubTator, text mining | PubMed |
| Phosphorylation destabilizes Per3 to promote gallbladder carcinoma. | Exp Cell Res | 2026 | 42777803 | PubTator, text mining | PubMed |
| Exploring the Impact of Urolithins A and B on Muscle Health: A Transcriptomic Analysis in Human Myotubes. | J Cachexia Sarcopenia Muscle | 2026 | 42773997 | PubTator, text mining | PubMed |
| Exploring causal associations between the plasma proteome and bone mineral density: a Mendelian randomization study. | Endocr Connect | 2026 | 42765911 | PubTator, text mining | PubMed |
| TGFBI Maintains Fibrocartilage Homeostasis by Restraining O-GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis. | Adv Sci (Weinh) | 2026 | 42750165 | PubTator, text mining | PubMed |
| RUNX3: a regulator of macrophage apoptosis with positive prognostic impact in sepsis. | Genes Genomics | 2026 | 42742904 | PubTator, text mining | PubMed |
| Cryo-EM structure of TGFBIp fibrils driven by a corneal dystrophy-linked mutation enables design of peptide inhibitors of aggregation. | Proc Natl Acad Sci U S A | 2026 | 42709813 | PubTator, text mining | PubMed |
| PUS7-Mediated Pseudouridylation of TGFBI Drives Vascular Remodeling in Pulmonary Hypertension. | Circulation | 2026 | 42677488 | PubTator, text mining | PubMed |
1 to 10 of 3,774
See all 3,774 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7045
GET https://conductscience.org/api/genes/v1/7045/patents?page=2