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Gene · 7045

TGFBI: transforming growth factor beta induced

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TGFBI: transforming growth factor beta induced. Genes, record 7045. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7045

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Gene

Symbol
TGFBI
HGNC
Name
transforming growth factor beta induced
HGNC
NCBI Gene ID
7045
NCBI Gene
HGNC ID
HGNC:11771
HGNC
Ensembl
ENSG00000120708
NCBI Gene
Aliases
BIGH3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, LCD1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15582Transforming growth factor-beta-induced protein ig-h368310Ensembl, GeneID, HGNC

Source UniProt

Patents156

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19369Q15582Espacenet
JP 2026004568 A2026-01-1467520Q15582Espacenet
JP 2026000906 A2026-01-0684Q15582Espacenet
EP 4650780 A22025-11-1914003Q15582Espacenet
EP 4641201 A22025-10-2916289Q15582Espacenet
EP 4641203 A22025-10-29495Q15582Espacenet
JP 2025147176 A2025-10-0613164Q15582Espacenet
JP 2025529142 A2025-09-047873Q15582Espacenet
US 12371689 B22025-07-297873Q15582Espacenet
JP 2025517967 A2025-06-12495Q15582Espacenet

1 to 10 of 156

See all 156 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,003

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTGFBI papersNewest fiscal year
P30CA016672Cancer Center Support Grant152025
P30CA015704Cancer Center Support Grant82025
P30EY000331Vision Research Core at UCLA82025
P30DK058404Molecular and Cellular Basis for Digestive Diseases72025
P30ES009089Center for Environmental Health in Northern Manhattan72025
P30CA068485Cancer Center Support Grant52025
P50CA127001SPORE in Brain Cancer52025
P50CA236733Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal Cancer52025
R01AI136946Mechanisms and consequence of helical shape generation in Helicobacter pylori52025
R01EY020581Role of Oxidative Stress in Pathogenesis of Fuchs Endothelial Corneal Dystrophy52025

1 to 10 of 2,003Source NIH's project files

See all 2,003 nih grants

Papers3,774

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Exosome-Mediated Bidirectional Signaling Regulates Glioma Stem-Cell Homeostasis and Radiation-Induced Plasticity.bioRxiv202642818566PubTator, text miningPubMed
Twist in the fibril: Structure guides inhibition of TGFBIp amyloid formation.Proc Natl Acad Sci U S A202642804651PubTator, text miningPubMed
A Novel Loss-of-Function Variant in TGFBI Associated with Non-Syndromic Orofacial Clefts in a Chinese Pedigree.Genes (Basel)202642792893PubTator, text miningPubMed
Phosphorylation destabilizes Per3 to promote gallbladder carcinoma.Exp Cell Res202642777803PubTator, text miningPubMed
Exploring the Impact of Urolithins A and B on Muscle Health: A Transcriptomic Analysis in Human Myotubes.J Cachexia Sarcopenia Muscle202642773997PubTator, text miningPubMed
Exploring causal associations between the plasma proteome and bone mineral density: a Mendelian randomization study.Endocr Connect202642765911PubTator, text miningPubMed
TGFBI Maintains Fibrocartilage Homeostasis by Restraining O-GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis.Adv Sci (Weinh)202642750165PubTator, text miningPubMed
RUNX3: a regulator of macrophage apoptosis with positive prognostic impact in sepsis.Genes Genomics202642742904PubTator, text miningPubMed
Cryo-EM structure of TGFBIp fibrils driven by a corneal dystrophy-linked mutation enables design of peptide inhibitors of aggregation.Proc Natl Acad Sci U S A202642709813PubTator, text miningPubMed
PUS7-Mediated Pseudouridylation of TGFBI Drives Vascular Remodeling in Pulmonary Hypertension.Circulation202642677488PubTator, text miningPubMed

1 to 10 of 3,774

See all 3,774 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7045

GET https://conductscience.org/api/genes/v1/7045/patents?page=2