Gene · 7051
TGM1: transglutaminase 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TGM1: transglutaminase 1. Genes, record 7051. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7051
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P22735 | Protein-glutamine gamma-glutamyltransferase K | 817 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents29
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 67559 | P22735 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 207 | P22735 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 207 | P22735 | Espacenet |
| US 11717547 B2 | 2023-08-08 | 5 | P22735 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 90222 | P22735 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 193193 | P22735 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 11512 | P22735 | Espacenet |
| US 10525090 B2 | 2020-01-07 | 5 | P22735 | Espacenet |
| WO 2019200163 A1 | 2019-10-17 | 5 | P22735 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 247994 | P22735 | Espacenet |
1 to 10 of 29
See all 29 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants834
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TGM1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| R01AR068392 | Genetics and Pathobiology of Disorders of Keratinization | 5 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P30CA134274 | UNIVERSITY OF MARYLAND GREENEBAUM CANCER CENTERSUPPORT GRANT | 4 | 2025 |
| R01AR043799 | Mechanisms of Epidermal Homeostasis and Early Neoplasia | 4 | 2025 |
| R01AR066530 | Regulators of epidermal growth and differentiation | 4 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 4 | 2025 |
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 4 | 2025 |
| I01BX004293 | CYP11A1-derived secosteroids as therapeutic agents in UVB induced skin cancer | 3 | 2025 |
1 to 10 of 834Source NIH's project files
See all 834 nih grantsPapers2,299
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Anoectochilus roxburghii extract alleviates inflammation and restores skin barrier function in vitro and in vivo. | Fitoterapia | 2026 | 42800590 | PubTator, text mining | PubMed |
| Genotypic and Phenotypic Profiles of Babies with Collodion Membrane in a Tertiary Care Center in Riyadh, Saudi Arabia. | Dermatology | 2026 | 42766467 | PubTator, text mining | PubMed |
| An efficient endogenous type I-E CRISPR-Cas genome-editing platform for producing transglutaminase in Streptomyces mobaraensis. | Eng Microbiol | 2026 | 42740853 | PubTator, text mining | PubMed |
| Cathepsin D as a central regulator of extracellular matrix remodeling in wound healing and chronic tissue pathologies. | Tissue Barriers | 2026 | 42720228 | PubTator, text mining | PubMed |
| Synergistic modification of soy protein isolate using transglutaminase and magnesium chloride: A sequential treatment strategy for dual allergenicity and digestibility benefits. | Food Chem | 2026 | 42659966 | PubTator, text mining | PubMed |
| Enzymatic double crosslinking strategy: remodeling of pea protein isolate hydrogels through transglutaminase and gelatin modification to redesign their functional properties. | Food Res Int | 2026 | 42637363 | PubTator, text mining | PubMed |
| Controlled thermal unfolding of soy protein isolate modulates transglutaminase-induced gelation and network structure of fish gelatin. | Food Chem | 2026 | 42594647 | PubTator, text mining | PubMed |
| Transglutaminase-mediated glycosylation of whey protein isolate with glucosamine: effects on structure, functional properties, and intestinal barrier function. | Food Chem X | 2026 | 42569495 | PubTator, text mining | PubMed |
| Modification of shrimp tropomyosin properties for improved functional performance: TGase modification and polyphenol-beta-glucan modification. | Food Chem | 2026 | 42551156 | PubTator, text mining | PubMed |
| Repetin Regulates Epidermal Barrier Homeostasis and Is Associated With Inflammatory Skin Diseases. | Exp Dermatol | 2026 | 42544840 | PubTator, text mining | PubMed |
1 to 10 of 2,299
See all 2,299 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7051
GET https://conductscience.org/api/genes/v1/7051/patents?page=2