ConductScience.org, home

Library / Genes

TGM2: transglutaminase 2

1 protein, 104 patents, 0 drugs, 0 trials, 2,828 NIH grants and 9,791 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTGM2HGNC
Nametransglutaminase 2HGNC
NCBI Gene ID7052NCBI Gene
HGNC IDHGNC:11778HGNC
EnsemblENSG00000198959NCBI Gene
AliasesG(h), TG(C), TG2, TGC, hTG2, tTGNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P21980Protein-glutamine gamma-glutamyltransferase 268713Ensembl, GeneID, HGNCUniProt

Patents 104

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467566P21980Espacenet
US 12502436 B22025-12-231725P21980Espacenet
JP 2025181835 A2025-12-111725P21980Espacenet
EP 4650780 A22025-11-198051P21980Espacenet
EP 4641201 A22025-10-298160P21980Espacenet
WO 2025199149 A12025-09-251725P21980Espacenet
KR 1020250117602 A2025-08-0518P21980Espacenet
JP 2025517969 A2025-06-128160P21980Espacenet
JP 2025517970 A2025-06-128051P21980Espacenet
KR 1020250076678 A2025-05-291725P21980Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2828

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01DK063158Role of Transglutaminase 2 in Celiac Sprue562,025NIH's project files
P30CA016672Cancer Center Support Grant222,025NIH's project files
R01DK032083Multiple Autoantigens, Multiple Epitopes of Type 1 Diabetes172,025NIH's project files
P30DK042086Center for Interdisciplinary Study of Inflammatory Intestinal DIsorders (C-IID)152,025NIH's project files
P30CA008748Cancer Center Support Grant102,025NIH's project files
R35GM150676Development of a Chemical Biology Toolbox to Investigate Histone Monoaminylation102,025NIH's project files
R01MH116900Molecular studies of neural histone monoaminylation in normal and aberrant brain plasticity92,025NIH's project files
P30DK017047Diabetes Research Center82,025NIH's project files
P30DK048520Colorado Nutrition Obesity Research Center82,025NIH's project files
P30EY010572Ophthalmology Core Facility82,025NIH's project files

Papers 9791

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824932PubTator, text miningPubMed
42820468PubTator, text miningPubMed
42815370PubTator, text miningPubMed
42812136PubTator, text miningPubMed
42811980PubTator, text miningPubMed
42807683PubTator, text miningPubMed
42804034PubTator, text miningPubMed
42800293PubTator, text miningPubMed
42792147PubTator, text miningPubMed
42787183PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license