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THBD: thrombomodulin

1 protein, 72 patents, 0 drugs, 0 trials, 4,627 NIH grants and 13,152 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTHBDHGNC
NamethrombomodulinHGNC
NCBI Gene ID7056NCBI Gene
HGNC IDHGNC:11784HGNC
EnsemblENSG00000178726NCBI Gene
AliasesAHUS6, BDCA-3, BDCA3, CD141, THPH12, THRM, TMNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P07204Thrombomodulin57513Ensembl, GeneID, HGNCUniProt

Patents 72

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2025262255 A12025-12-2638P07204Espacenet
EP 4650780 A22025-11-199882P07204Espacenet
JP 2025169942 A2025-11-141317P07204Espacenet
JP 2025529142 A2025-09-044662P07204Espacenet
US 12371689 B22025-07-294662P07204Espacenet
JP 2025517970 A2025-06-129882P07204Espacenet
US 11446398 B22022-09-2088584P07204Espacenet
US 11400116 B22022-08-02108P07204Espacenet
JP 2022524081 A2022-04-27191555P07204Espacenet
US 11078247 B22021-08-0311527P07204Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4627

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01HL049413Structural basis of prothrombin activation322,025NIH's project files
P30CA008748Cancer Center Support Grant302,025NIH's project files
R01HL101917Protease Activated Receptor and Thrombomodulin Signaling by coagulation proteases232,025NIH's project files
P30CA016672Cancer Center Support Grant192,025NIH's project files
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success182,025NIH's project files
P01AI045897A Tolerance Approach to Xenotransplantation172,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award132,025NIH's project files
T32GM008315Mechanisms of Trauma-Induced Coagulopathy122,025NIH's project files
R01HL101972Characterization of Coagulation Factor-platelet Interactions: Role of FXI112,025NIH's project files
T32HL007088Pre-and Postgraduate Training in Molecular Hematology112,025NIH's project files

Papers 13152

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42809655PubTator, text miningPubMed
42808109PubTator, text miningPubMed
42793237PubTator, text miningPubMed
42789340PubTator, text miningPubMed
42783752PubTator, text miningPubMed
42783235PubTator, text miningPubMed
42782740PubTator, text miningPubMed
42779682PubTator, text miningPubMed
42767899PubTator, text miningPubMed
42766148PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license