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THBS1: thrombospondin 1

1 protein, 163 patents, 0 drugs, 0 trials, 7,265 NIH grants and 14,429 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTHBS1HGNC
Namethrombospondin 1HGNC
NCBI Gene ID7057NCBI Gene
HGNC IDHGNC:11785HGNC
EnsemblENSG00000137801NCBI Gene
AliasesTHBS, THBS-1, TSP, TSP-1, TSP1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P07996Thrombospondin-11,17011Ensembl, GeneID, HGNCUniProt

Patents 163

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026090543 A2026-06-02398P07996Espacenet
US 12534732 B22026-01-277P07996Espacenet
JP 2026012378 A2026-01-237P07996Espacenet
US 12516329 B22026-01-067P07996Espacenet
EP 4670792 A22025-12-317P07996Espacenet
KR 1020250175016 A2025-12-164P07996Espacenet
EP 4650780 A22025-11-191796P07996Espacenet
KR 1020250160362 A2025-11-127P07996Espacenet
EP 4641201 A22025-10-291381P07996Espacenet
JP 2025147176 A2025-10-0613190P07996Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 7265

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant482,025NIH's project files
P30EY016665Core Grant for Vision Research292,025NIH's project files
P30EY003790Core Grant for Vision Research232,025NIH's project files
R01HL076246Chemokines in healing myocardial infarction212,025NIH's project files
P30CA008748Cancer Center Support Grant202,025NIH's project files
R01HL085440Resolution of inflammation in healing myocardial infarcts202,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support192,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award182,025NIH's project files
R01EY005665Corneal Epithelial-Stromal Interactions During Regeneration and Fibrosis152,025NIH's project files
P30CA006973Regional Oncology Research Center132,025NIH's project files

Papers 14429

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818566PubTator, text miningPubMed
42818339PubTator, text miningPubMed
42811239PubTator, text miningPubMed
42807007PubTator, text miningPubMed
42801549PubTator, text miningPubMed
42794505PubTator, text miningPubMed
42781206PubTator, text miningPubMed
42778431PubTator, text miningPubMed
42770305PubTator, text miningPubMed
42759654PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license