Gene · 7058
THBS2: thrombospondin 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. THBS2: thrombospondin 2. Genes, record 7058. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7058
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P35442 | Thrombospondin-2 | 1,172 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents79
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 8112 | P35442 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 1229 | P35442 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8257 | P35442 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 13192 | P35442 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 13193 | P35442 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7877 | P35442 | Espacenet |
| EP 4606428 A2 | 2025-08-27 | 4 | P35442 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7877 | P35442 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 1229 | P35442 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8257 | P35442 | Espacenet |
1 to 10 of 79
See all 79 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,850
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | THBS2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA014520 | UW Comprehensive Cancer Center Support | 14 | 2025 |
| P30EY016665 | Core Grant for Vision Research | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 13 | 2025 |
| P30DK040561 | Boston Area Nutrition Obesity Research Center (NORC) | 7 | 2025 |
| R01CA164719 | Anti-cancer vaccine targeting the host-parasite interface during fluke infection | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| R01HL076246 | Chemokines in healing myocardial infarction | 5 | 2025 |
| U01CA200468 | Clinical Validation Center for Early Detection of Pancreatic Cancer | 5 | 2025 |
| U01CA210240 | Pancreatic Cancer Detection Consortium | 5 | 2025 |
| U10CA180821 | Alliance for Clinical Trials in Oncology Operations Center - GY11 Funded Extension | 5 | 2025 |
1 to 10 of 1,850Source NIH's project files
See all 1,850 nih grantsPapers3,211
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Reduced vascular function, ventilatory efficiency and exercise capacity in young adult electronic cigarette users. | ERJ Open Res | 2026 | 42807821 | PubTator, text mining | PubMed |
| The Role of Thrombospondin-2 in Myocardial Fibrosis. | Drug Des Devel Ther | 2026 | 42787207 | PubTator, text mining | PubMed |
| Circulating angiogenic and inflammatory biomarkers profiling in patients with hereditary hemorrhagic telangiectasia. | Eur J Intern Med | 2026 | 42778431 | PubTator, text mining | PubMed |
| Conserved hepatic RNA signatures across multiple cohorts reveal novel mechanistic clues for advanced fibrosis in human MASLD. | Hepatol Commun | 2026 | 42748406 | PubTator, text mining | PubMed |
| Markers of microvascular instability predict severity and survival in idiopathic pulmonary fibrosis. | Thorax | 2026 | 42722423 | PubTator, text mining | PubMed |
| Proteomic Profiling of Breast Implant Capsules: a Novel Approach for Studying Biocompatibility and Capsular Contracture. | Aesthet Surg J | 2026 | 42717641 | PubTator, text mining | PubMed |
| From sebocytes to skin engineering human sebaceous organoids within a reconstructed dermal matrix. | Front Toxicol | 2026 | 42598348 | PubTator, text mining | PubMed |
| Myofibroblastic CAF and Malignant Ductal Cell Crosstalk Drives Epithelial-Mesenchymal Transition and Progression in Pancreatic Ductal Adenocarcinoma via THBS2-SDC/Integrin Axes. | Int J Mol Sci | 2026 | 42589604 | PubTator, text mining | PubMed |
| Down-regulation of THBS2 inhibits the malignant progression of Burkitt lymphoma by blocking the PI3K/AKT/c-MYC pathway. | Front Oncol | 2026 | 42568393 | PubTator, text mining | PubMed |
| Proteomic Mediators of Chronic Obstructive Pulmonary Disease Phenotypes and Coronary Artery Calcification Burden in Ever Smokers. | J Am Heart Assoc | 2026 | 42568067 | PubTator, text mining | PubMed |
1 to 10 of 3,211
See all 3,211 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7058
GET https://conductscience.org/api/genes/v1/7058/patents?page=2