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TSPO: translocator protein

2 proteins, 46 patents, 3 drugs, 5 trials, 2,739 NIH grants and 5,028 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTSPOHGNC
Nametranslocator proteinHGNC
NCBI Gene ID706NCBI Gene
HGNC IDHGNC:1158HGNC
EnsemblENSG00000100300NCBI Gene
AliasesBPBS, BZRP, DBI, IBP, MBR, PBR, PBS, PKBS, PTBR, TSPO1, mDRC, pk18NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 2

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
B1AH88Putative peripheral benzodiazepine receptor-related protein1020HGNCUniProt
P30536Translocator protein1690Ensembl, GeneID, HGNCUniProt

Patents 46

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467719P30536Espacenet
JP 2026004568 A2026-01-1467720P30536Espacenet
JP 2026004568 A2026-01-1467721B1AH88Espacenet
EP 4650780 A22025-11-195792P30536Espacenet
JP 2025529142 A2025-09-045110P30536Espacenet
US 12371689 B22025-07-295110P30536Espacenet
JP 2025517970 A2025-06-125792P30536Espacenet
US 12161663 B22024-12-101P30536Espacenet
JP 2023548225 A2023-11-152P30536Espacenet
US 11446398 B22022-09-2090553P30536Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ALPIDEMCHEMBL54349Translocator protein partial agonistPARTIAL AGONISTChEMBL
EMAPUNILCHEMBL513922Translocator protein agonistAGONISTChEMBL
ONO-2952CHEMBL4297311Translocator protein antagonistANTAGONISTChEMBL

Trials 5

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07191821EMAPUNILPHASE2ClinicalTrials.gov
NCT06643013EMAPUNILClinicalTrials.gov
NCT06035861EMAPUNILClinicalTrials.gov
NCT03850301EMAPUNILClinicalTrials.gov
NCT00108836EMAPUNILPHASE2ClinicalTrials.gov

NIH grants 2739

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAMH002793PET Radiopharmaceutical Sciences492,025NIH's project files
ZIAMH002852Clinical Evaluation of PET Radiotracers372,025NIH's project files
ZIAMH002795Translational Evaluation of PET Radiotracers282,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award182,025NIH's project files
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study82,025NIH's project files
P30AG062421Massachusetts Alzheimer's Disease Research Center (MADRC)82,025NIH's project files
P30ES009089Center for Environmental Health in Northern Manhattan82,025NIH's project files
P41EB024495Resource for Molecular Imaging Agents in Precision Medicine72,025NIH's project files
R28AA012725Brain Tissue Resource Center for Alcohol Research72,025NIH's project files
P30AG066462Alzheimer's Disease Research Center62,025NIH's project files

Papers 5028

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42814343PubTator, text miningPubMed
42809445PubTator, text miningPubMed
42756215PubTator, text miningPubMed
42751212PubTator, text miningPubMed
42723412PubTator, text miningPubMed
42685155PubTator, text miningPubMed
42683863PubTator, text miningPubMed
42676908PubTator, text miningPubMed
42658184PubTator, text miningPubMed
42653340PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license