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TIAM1: TIAM Rac1 associated GEF 1
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Gene · 7074

Papers2,121

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

41 to 60 of 2,121

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TitleJournalYearPMIDFound bySource
Evaluating the Causal Association between Circulating Plasma Proteins, 731 Immune Cell Phenotypes, and Atopic Dermatitis: A Mediation Mendelian Randomization Study.Int Arch Allergy Immunol202539536725PubTator, text miningPubMed
Exploiting fly models to investigate rare human neurological disorders.Neural Regen Res202538767473PubTator, text miningPubMed
Tiam1 Mediated Enhancement of AKT/mTOR and ERK/STAT3 Signaling Promotes Proliferation, Invasion and Migration of Pancreatic Cancer.Ann Clin Lab Sci202439855727PubTator, text miningPubMed
Guanine nucleotide exchange factors and colon neoplasia.Front Cell Dev Biol202439493347PubTator, text miningPubMed
Novel inhibitor against Rac1 for therapeutic approach in prevention of breast cancer progression.Sci Rep202439443601PubTator, text miningPubMed
Proteogenomic Landscape of Breast Ductal Carcinoma Reveals Tumor Progression Characteristics and Therapeutic Targets.Adv Sci (Weinh)202439418072PubTator, text miningPubMed
The scaffold protein IQGAP1 promotes reorientation of epithelial cell polarity at the two-cell stage for cystogenesis.Genes Cells202439377417PubTator, text miningPubMed
The analysis on Tiam2 for expression in esophageal carcinoma: A descriptive study.Medicine (Baltimore)202439093764PubTator, text miningPubMed
The S-Nitrosylation of Septin2 (SNO-Septin2) axis: A novel potential therapeutic target for treating aneurysms and dissection.Drug Discov Ther202438987209PubTator, text miningPubMed
[Whole Exome Sequencing Reveals Gene Mutation Characteristics of Primary Central Nervous System Lymphoma].Zhongguo Shi Yan Xue Ye Xue Za Zhi202438926963PubTator, text miningPubMed
RhoGEF Tiam2 Regulates Glutamatergic Synaptic Transmission in Hippocampal CA1 Pyramidal Neurons.eNeuro202438871458PubTator, text miningPubMed
Decreased Tiam1-mediated Rac1 activation is responsible for impaired directional persistence of chondrocyte migration in microtia.J Cell Mol Med202438837873PubTator, text miningPubMed
Tiam1 is part of a novel mechanism for morphine tolerance and hyperalgesia.Brain202438805748PubTator, text miningPubMed
Tiam1-mediated maladaptive plasticity underlying morphine tolerance and hyperalgesia.Brain202438577773PubTator, text miningPubMed
The Legionella pneumophila effector DenR hijacks the host NRas proto-oncoprotein to downregulate MAPK signaling.Cell Rep202438568811PubTator, text miningPubMed
Genomic analysis of 116 autism families strengthens known risk genes and highlights promising candidates.NPJ Genom Med202438519481PubTator, text miningPubMed
Tiam1 regulates proliferation, invasion, and differentiation in neuroblastoma through the Tiam1/Rac1 signaling pathway.Neoplasma202438506031PubTator, text miningPubMed
S-Nitrosylation of Septin2 Exacerbates Aortic Aneurysm and Dissection by Coupling the TIAM1-RAC1 Axis in Macrophages.Circulation202438357802PubTator, text miningPubMed
14-3-3ε: a protein with complex physiology function but promising therapeutic potential in cancer.Cell Commun Signal202438279176PubTator, text miningPubMed
Myocardial Oedema as a Consequence of Viral Infection and Persistence-A Narrative Review with Focus on COVID-19 and Post COVID Sequelae.Viruses202438257821PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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