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TIMP3: TIMP metallopeptidase inhibitor 3

1 protein, 143 patents, 0 drugs, 0 trials, 3,553 NIH grants and 7,429 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTIMP3HGNC
NameTIMP metallopeptidase inhibitor 3HGNC
NCBI Gene ID7078NCBI Gene
HGNC IDHGNC:11822HGNC
EnsemblENSG00000100234NCBI Gene
AliasesHSMRK222, K222, K222TA2, SFDNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P35625Metalloproteinase inhibitor 32111Ensembl, GeneID, HGNCUniProt

Patents 143

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2024219974 A52026-07-1728P35625Espacenet
JP 2026515744 A2026-05-19293P35625Espacenet
US 12539325 B22026-02-0316P35625Espacenet
US 12534732 B22026-01-27927P35625Espacenet
JP 2026012378 A2026-01-23927P35625Espacenet
JP 2026004409 A2026-01-142P35625Espacenet
US 12516329 B22026-01-06927P35625Espacenet
EP 4670792 A22025-12-31927P35625Espacenet
EP 4650780 A22025-11-192558P35625Espacenet
KR 1020250160362 A2025-11-12927P35625Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3553

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant172,025NIH's project files
P30EY014800University of Utah Core Vision Research Grant122,025NIH's project files
P30CA016058Cancer Center Support Grant112,025NIH's project files
P30EY005722Center Core Grant for Vision Research102,025NIH's project files
P30EY025585NEI Center Core Grant for Vision Research102,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award102,025NIH's project files
P30CA014520UW Comprehensive Cancer Center Support82,025NIH's project files
P30CA008748Cancer Center Support Grant72,025NIH's project files
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant72,025NIH's project files
P30CA015704Cancer Center Support Grant72,025NIH's project files

Papers 7429

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42717641PubTator, text miningPubMed
42712869PubTator, text miningPubMed
42656980PubTator, text miningPubMed
42653642PubTator, text miningPubMed
42614256PubTator, text miningPubMed
42589624PubTator, text miningPubMed
42569289PubTator, text miningPubMed
42539139PubTator, text miningPubMed
42537860PubTator, text miningPubMed
42517396PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license