ConductScience.org, home

Gene · 7079

TIMP4: TIMP metallopeptidase inhibitor 4

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. TIMP4: TIMP metallopeptidase inhibitor 4. Genes, record 7079. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7079

On this page

Gene

Symbol
TIMP4
HGNC
Name
TIMP metallopeptidase inhibitor 4
HGNC
NCBI Gene ID
7079
NCBI Gene
HGNC ID
HGNC:11823
HGNC
Ensembl
ENSG00000157150
NCBI Gene
Aliases
TIMP-4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q99727Metalloproteinase inhibitor 42240Ensembl, GeneID, HGNC

Source UniProt

Patents86

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
US 12539325 B22026-02-0317Q99727Espacenet
EP 4650780 A22025-11-193341Q99727Espacenet
EP 4641201 A22025-10-292909Q99727Espacenet
JP 2025147176 A2025-10-0613248Q99727Espacenet
JP 2025529142 A2025-09-047889Q99727Espacenet
US 12371689 B22025-07-297889Q99727Espacenet
JP 2025517969 A2025-06-122909Q99727Espacenet
JP 2025517970 A2025-06-123341Q99727Espacenet
JP 2025028160 A2025-02-2813248Q99727Espacenet
KR 1020250010750 A2025-01-2113248Q99727Espacenet

1 to 10 of 86

See all 86 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,021

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTIMP4 papersNewest fiscal year
ZIAAI001065India International Center for Excellence in Research72025
U54GM115428Mississippi Center for Clinical and Translational Research42025
P30EY011373CWRU NEI Vision Center Core Grant32025
P30EY016665Core Grant for Vision Research32025
P30CA008748Cancer Center Support Grant22025
P30CA016672Cancer Center Support Grant22025
P30CA042014Cancer Center Support Grant22025
P30CA047904Cancer Center Support Grant22025
P30CA177558University of Kentucky Markey Cancer Center – Cancer Center Support Grant22025
P30EY014104P30 Core Grant for Vision Research22025

1 to 10 of 1,021Source NIH's project files

See all 1,021 nih grants

Papers1,944

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Cross-Species Transcriptomic Integration Identifies a Conserved Molecular Core and Regulatory ceRNA Network in Duchenne Muscular Dystrophy.Genes (Basel)202642792910PubTator, text miningPubMed
Blood protein biomarkers for rheumatoid arthritis patients complicated by interstitial lung disease.Front Med (Lausanne)202642657074PubTator, text miningPubMed
Bioinformatic identification of THY1 as a target in osteoarthritis and its effects on chondrocyte senescence and apoptosis.Funct Integr Genomics202642640506PubTator, text miningPubMed
Neuroinflammation- molecular target based therapeutic approach.Adv Protein Chem Struct Biol202642448410PubTator, text miningPubMed
Epigenetic regulation of cardiac physiology and pathophysiology: biological sex matters.J Cardiovasc Aging202642369572PubTator, text miningPubMed
Atrial Fibrillation, Cerebral Small Vessel Disease and Gender Medicine: Focus on Biomarkers and Neuroimaging.J Clin Med202642355595PubTator, text miningPubMed
Machine-Learning Approach to Identify Tissue Inhibitors of Metalloproteinases (TIMP) and Clinical Variables Predicting Executive Phenotypes in HIV-infected Adults.Open Forum Infect Dis202642272922PubTator, text miningPubMed
Look what you make my tissues do: The role of metalloproteinases and their inhibitors in Bothrops snakebites.PLoS Negl Trop Dis202642030365PubTator, text miningPubMed
A machine learning model for periodontitis based on integrative gene expression analysis: validation in an independent patient cohort.J Periodontal Implant Sci202641968714PubTator, text miningPubMed
Inflammatory profile of diabetic ketoacidosis in children with type 1 diabetes.BMJ Open Diabetes Res Care202641807017PubTator, text miningPubMed

1 to 10 of 1,944

See all 1,944 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7079

GET https://conductscience.org/api/genes/v1/7079/patents?page=2