Gene · 7079
TIMP4: TIMP metallopeptidase inhibitor 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TIMP4: TIMP metallopeptidase inhibitor 4. Genes, record 7079. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7079
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q99727 | Metalloproteinase inhibitor 4 | 224 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents86
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12539325 B2 | 2026-02-03 | 17 | Q99727 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3341 | Q99727 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2909 | Q99727 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 13248 | Q99727 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7889 | Q99727 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7889 | Q99727 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2909 | Q99727 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3341 | Q99727 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 13248 | Q99727 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 13248 | Q99727 | Espacenet |
1 to 10 of 86
See all 86 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,021
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TIMP4 papers | Newest fiscal year |
|---|---|---|---|
| ZIAAI001065 | India International Center for Excellence in Research | 7 | 2025 |
| U54GM115428 | Mississippi Center for Clinical and Translational Research | 4 | 2025 |
| P30EY011373 | CWRU NEI Vision Center Core Grant | 3 | 2025 |
| P30EY016665 | Core Grant for Vision Research | 3 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 2 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 2 | 2025 |
| P30CA042014 | Cancer Center Support Grant | 2 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 2 | 2025 |
| P30CA177558 | University of Kentucky Markey Cancer Center – Cancer Center Support Grant | 2 | 2025 |
| P30EY014104 | P30 Core Grant for Vision Research | 2 | 2025 |
1 to 10 of 1,021Source NIH's project files
See all 1,021 nih grantsPapers1,944
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Cross-Species Transcriptomic Integration Identifies a Conserved Molecular Core and Regulatory ceRNA Network in Duchenne Muscular Dystrophy. | Genes (Basel) | 2026 | 42792910 | PubTator, text mining | PubMed |
| Blood protein biomarkers for rheumatoid arthritis patients complicated by interstitial lung disease. | Front Med (Lausanne) | 2026 | 42657074 | PubTator, text mining | PubMed |
| Bioinformatic identification of THY1 as a target in osteoarthritis and its effects on chondrocyte senescence and apoptosis. | Funct Integr Genomics | 2026 | 42640506 | PubTator, text mining | PubMed |
| Neuroinflammation- molecular target based therapeutic approach. | Adv Protein Chem Struct Biol | 2026 | 42448410 | PubTator, text mining | PubMed |
| Epigenetic regulation of cardiac physiology and pathophysiology: biological sex matters. | J Cardiovasc Aging | 2026 | 42369572 | PubTator, text mining | PubMed |
| Atrial Fibrillation, Cerebral Small Vessel Disease and Gender Medicine: Focus on Biomarkers and Neuroimaging. | J Clin Med | 2026 | 42355595 | PubTator, text mining | PubMed |
| Machine-Learning Approach to Identify Tissue Inhibitors of Metalloproteinases (TIMP) and Clinical Variables Predicting Executive Phenotypes in HIV-infected Adults. | Open Forum Infect Dis | 2026 | 42272922 | PubTator, text mining | PubMed |
| Look what you make my tissues do: The role of metalloproteinases and their inhibitors in Bothrops snakebites. | PLoS Negl Trop Dis | 2026 | 42030365 | PubTator, text mining | PubMed |
| A machine learning model for periodontitis based on integrative gene expression analysis: validation in an independent patient cohort. | J Periodontal Implant Sci | 2026 | 41968714 | PubTator, text mining | PubMed |
| Inflammatory profile of diabetic ketoacidosis in children with type 1 diabetes. | BMJ Open Diabetes Res Care | 2026 | 41807017 | PubTator, text mining | PubMed |
1 to 10 of 1,944
See all 1,944 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7079
GET https://conductscience.org/api/genes/v1/7079/patents?page=2