Gene · 7086
TKT: transketolase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TKT: transketolase. Genes, record 7086. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7086
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P29401 | Transketolase | 623 | 13 | Ensembl, GeneID, HGNC |
Source UniProt
Patents58
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026063308 A | 2026-03-26 | 28 | P29401 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 67679 | P29401 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 67680 | P29401 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 13343 | P29401 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 15179 | P29401 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 6617 | P29401 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 15179 | P29401 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 13343 | P29401 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 6617 | P29401 | Espacenet |
| WO 2024240908 A1 | 2024-11-28 | 13 | P29401 | Espacenet |
1 to 10 of 58
See all 58 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,450
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TKT papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| P30CA177558 | University of Kentucky Markey Cancer Center – Cancer Center Support Grant | 9 | 2025 |
| P20GM121327 | University of Kentucky Center for Cancer Metabolism | 6 | 2025 |
| P30ES013508 | Center of Excellence in Environmental Toxicology | 4 | 2025 |
| R01AA005965 | CNS Deficits: Interaction of Age and Alcoholism | 4 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 3 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 3 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 3 | 2025 |
| R01HL086694 | From GWAS loci to blood pressure genes, variants & mechanisms - Renewal | 3 | 2025 |
1 to 10 of 1,450Source NIH's project files
See all 1,450 nih grantsPapers3,154
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A general method for the assay of thiamine pyrophosphokinase activity. | Methods Enzymol | 2026 | 42778273 | PubTator, text mining | PubMed |
| Protocol for the measurement of human brain transketolase activity. | Methods Enzymol | 2026 | 42778272 | PubTator, text mining | PubMed |
| Assessment of thiamine status in humans. | Methods Enzymol | 2026 | 42778271 | PubTator, text mining | PubMed |
| Transketolase promotes RNF20-dependent H2BK120 ubiquitination and DNA repair through a non-enzymatic adaptor function. | FEBS J | 2026 | 42713978 | PubTator, text mining | PubMed |
| Exploring Inhibitory Impacts of Anamorelin on Colorectal Cancer Proliferation via Regulation of Transketolase. | Curr Med Chem | 2026 | 42693844 | PubTator, text mining | PubMed |
| Thiamine diphosphate-dependent enzymes: mechanistic principles, stereoselective C-C bond formation, and synthetic biocatalytic applications. | Org Biomol Chem | 2026 | 42638609 | PubTator, text mining | PubMed |
| Chronic Stress-Induced m7G Cap Modification of ADRB2 Dysregulates the Pentose Phosphate Pathway to Promote Esophageal Squamous Cell Carcinoma Progression. | Cancer Res | 2026 | 42555660 | PubTator, text mining | PubMed |
| TKTL1 mediates metabolic adaptation and stress resistance in pancreatic cancer cells under nutrient-deprived conditions. | Oncogene | 2026 | 42533116 | PubTator, text mining | PubMed |
| Systematic review of extracellular vesicle-based liquid biopsy for leptomeningeal metastasis: current evidence and future directions. | Clin Exp Metastasis | 2026 | 42484930 | PubTator, text mining | PubMed |
| Targeting TKT-associated immunometabolic remodeling attenuates experimental lupus nephritis and NET-related inflammation. | Front Cell Dev Biol | 2026 | 42459832 | PubTator, text mining | PubMed |
1 to 10 of 3,154
See all 3,154 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7086
GET https://conductscience.org/api/genes/v1/7086/patents?page=2