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Gene · 7094

TLN1: talin 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TLN1: talin 1. Genes, record 7094. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7094

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Gene

Symbol
TLN1
HGNC
Name
talin 1
HGNC
NCBI Gene ID
7094
NCBI Gene
HGNC ID
HGNC:11845
HGNC
Ensembl
ENSG00000137076
NCBI Gene
Aliases
ILWEQ, TLN, talin-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9Y490Talin-12,5414Ensembl, GeneID, HGNC

Source UniProt

Patents50

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195047Q9Y490Espacenet
EP 4641201 A22025-10-294625Q9Y490Espacenet
JP 2025517969 A2025-06-124625Q9Y490Espacenet
JP 2025517970 A2025-06-125047Q9Y490Espacenet
JP 2024123008 A2024-09-108604Q9Y490Espacenet
EP 4373841 A12024-05-2951Q9Y490Espacenet
JP 2024009871 A2024-01-23105Q9Y490Espacenet
US 11694765 B22023-07-04372Q9Y490Espacenet
JP 2023064789 A2023-05-1275Q9Y490Espacenet
WO 2023074712 A2023-05-0421Q9Y490Espacenet

1 to 10 of 50

See all 50 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,212

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTLN1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant82025
P30CA008748Cancer Center Support Grant62025
R01CA085862Adhesive regulation during cell migration52025
T32HL007829Training Program in Lung Biology and Pathobiology42025
I01BX002196lntegrin binding proteins and the kidney32025
P01CA254849Integrated Immune Engineering for Poor Prognosis Cancers32025
P30CA014520UW Comprehensive Cancer Center Support32025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30CA033572Cancer Center Support Grant32025
P30DK058404Molecular and Cellular Basis for Digestive Diseases32025

1 to 10 of 1,212Source NIH's project files

See all 1,212 nih grants

Papers1,871

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Outside-In Signaling as a Detonator-like Stimulus of Integrin Activation by Promoting Both Affinity and Avidity.Biomolecules202642793190PubTator, text miningPubMed
The impact of low carbohydrate diet on the plasma proteomic profile of individuals with obesity.Front Nutr202642780918PubTator, text miningPubMed
Retraction Note: Identification of TLN1 as a prognostic biomarker to effect cell proliferation and differentiation in acute myeloid leukemia.BMC Cancer202642693420PubTator, text miningPubMed
A versatile AuNPs@UiO-66-based electrochemiluminescent immunosensing platform for sensitive detection of talin proteins.Mikrochim Acta202642663686PubTator, text miningPubMed
XGBoost-SHAP Interpretable Modeling Identifies and Validates an Eight-Gene Biomarker for Hepatic Encephalopathy Risk Prediction in Cirrhosis.Int J Mol Sci202642589578PubTator, text miningPubMed
DIA-based serum proteomics of the complement-coagulation cascade identifies candidate biomarkers for myasthenia gravis.Front Neurosci202642516550PubTator, text miningPubMed
Integrative Proteomics and Phosphoproteomics Profiling of Chronic Enteropathy Associated with SLCO2A1 Gene Reveals Mucosal Barrier Impairment and Focal Adhesion Pathway Alterations.Biomedicines202642511887PubTator, text miningPubMed
A vesicular trafficking pathway mediated by N-ethylmaleimide-sensitive factor governs integrin maturation and podocyte integrity.Kidney Int202642492856PubTator, text miningPubMed
Effect of calcium and magnesium ion incorporation on the osteogenic differentiation of human MSCs on SLA-treated titanium implant surfaces.J Oral Sci202642457556PubTator, text miningPubMed
Corrigendum to "Rap1 organizes lymphocyte front-back polarity via RhoA signaling and talin1" [iScience, Volume 26, Issue 8 (2023) 107292].iScience202642436987PubTator, text miningPubMed

1 to 10 of 1,871

See all 1,871 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7094

GET https://conductscience.org/api/genes/v1/7094/patents?page=2