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TLR1: toll like receptor 1

1 protein, 82 patents, 0 drugs, 0 trials, 3,266 NIH grants and 5,802 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTLR1HGNC
Nametoll like receptor 1HGNC
NCBI Gene ID7096NCBI Gene
HGNC IDHGNC:11847HGNC
EnsemblENSG00000174125NCBI Gene
AliasesCD281, KIAA0012, TIL, TIL. LPRS5, rsc786NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q15399Toll-like receptor 17866Ensembl, GeneID, HGNCUniProt

Patents 82

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467217Q15399Espacenet
JP 2026004568 A2026-01-1467218Q15399Espacenet
EP 4650780 A22025-11-197972Q15399Espacenet
EP 4640849 A22025-10-291206Q15399Espacenet
EP 4641201 A22025-10-298074Q15399Espacenet
JP 2025147176 A2025-10-0613267Q15399Espacenet
JP 2025147176 A2025-10-0613268Q15399Espacenet
JP 2025529142 A2025-09-044678Q15399Espacenet
JP 2025529142 A2025-09-047893Q15399Espacenet
US 12371689 B22025-07-294678Q15399Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3266

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant142,025NIH's project files
U19AI089992Immune signatures of vaccine responses in vulnerable populations132,025NIH's project files
P30AG021342Claude D. Pepper Older Americans Independence Center at Yale112,025NIH's project files
R01AI022553Molecular Analysis of Host Immune Response in Leprosy102,025NIH's project files
R01AR040312CD1-restricted T-cell Responses in Skin102,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital92,025NIH's project files
P30CA008748Cancer Center Support Grant72,025NIH's project files
ZIAAI000197Immunoregulation /Immune Recognition In Filarial/Nonfilarial Parasitic Infection62,025NIH's project files
P30AI036219Rustbelt Center for AIDS Research (Case/UHC-Pitt CFAR)52,025NIH's project files
T32AR007258Research Training in Rheumatology at Massachusetts General Hospital52,025NIH's project files

Papers 5802

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42792818PubTator, text miningPubMed
42688675PubTator, text miningPubMed
42650137PubTator, text miningPubMed
42542193PubTator, text miningPubMed
42480453PubTator, text miningPubMed
42457013PubTator, text miningPubMed
42446133PubTator, text miningPubMed
42445175PubTator, text miningPubMed
42438590PubTator, text miningPubMed
42424932PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license