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Gene · 71

ACTG1: actin gamma 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ACTG1: actin gamma 1. Genes, record 71. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/71

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Gene

Symbol
ACTG1
HGNC
Name
actin gamma 1
HGNC
NCBI Gene ID
71
NCBI Gene
HGNC ID
HGNC:144
HGNC
Ensembl
ENSG00000184009
NCBI Gene
Aliases
ACT, ACTG, DFNA20, DFNA26, HEL-176
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P63261Actin, cytoplasmic 237511Ensembl, GeneID, HGNC

Source UniProt

Patents144

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1917273P63261Espacenet
EP 4641201 A22025-10-2921316P63261Espacenet
JP 2025517969 A2025-06-1221316P63261Espacenet
JP 2025517970 A2025-06-1217273P63261Espacenet
JP 2025062604 A2025-04-141449P63261Espacenet
JP 2025062604 A2025-04-141450P63261Espacenet
JP 2025062604 A2025-04-141451P63261Espacenet
JP 2025062604 A2025-04-141453P63261Espacenet
JP 2025062604 A2025-04-141457P63261Espacenet
JP 2025062604 A2025-04-141460P63261Espacenet

1 to 10 of 144

See all 144 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,616

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleACTG1 papersNewest fiscal year
R01DC012049Optimizing Genetic Testing for Deafness for Clinical Diagnostics112025
P30CA008748Cancer Center Support Grant62025
R01NS058721ACC: Callosal Agenesis as a Window into Common Neurodevelopmental Disorders62025
UM1AI068636Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections62025
P30AI060354Harvard University Center for AIDS Research52025
UM1AI068634Statistical and Data Management Center (SDMC), Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections (ACTG)52025
UM1AI069494Pitt-Ohio State Clinical Trials Unit52025
P30AI050410The University of North Carolina Center for AIDS Research42025
P30AI073961Miami Center for AIDS Research42025
P30CA016672Cancer Center Support Grant42025

1 to 10 of 1,616Source NIH's project files

See all 1,616 nih grants

Papers2,039

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Top-Down Proteomics in the Assessment of Kidney Donor Quality: A Proof of Concept for Increased Organ Utilization.Mol Cell Proteomics202642759700PubTator, text miningPubMed
Adaptive design strategies for ethical and efficient clinical trials using simulated annealing.Stat Methods Med Res202642736680PubTator, text miningPubMed
A Novel Mutation in ACTG1 as the Probable Cause of Nonsyndromic Hearing Loss in Chinese Han Population.Neural Plast202642657483PubTator, text miningPubMed
In-depth monitoring of host cell proteins in influenza vaccines throughout multi-step purification processes.Vaccine202642501716PubTator, text miningPubMed
MiT fusions, TSC1-TSC2 divergence, and stem-like programs reveal distinct origins and vulnerabilities in PEComa.Nat Commun202642331846PubTator, text miningPubMed
3'UTR regulation of axon translation and optic nerve regeneration.Mol Neurodegener202642216210PubTator, text miningPubMed
Tumor cell-derived HSP47 promotes pancreatic Cancer metastasis via Homotrimeric collagen-mediated M2 macrophage polarization.Cell Signal202642128153PubTator, text miningPubMed
[Overview of cytoskeletal actin mutations associated with rare diseases].Orv Hetil202642107038PubTator, text miningPubMed
Expression of sulfate pathway genes in human neurodevelopment.J Neurogenet202642101182PubTator, text miningPubMed
From genes to clinical application: a circulating four-gene signature for early diagnosis model of refractory Mycoplasma pneumoniae pneumonia.Front Cell Infect Microbiol202642022810PubTator, text miningPubMed

1 to 10 of 2,039

See all 2,039 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/71

GET https://conductscience.org/api/genes/v1/71/patents?page=2