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Gene · 710

SERPING1: serpin family G member 1

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. SERPING1: serpin family G member 1. Genes, record 710. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/710

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
SERPING1
HGNC
Name
serpin family G member 1
HGNC
NCBI Gene ID
710
NCBI Gene
HGNC ID
HGNC:1228
HGNC
Ensembl
ENSG00000149131
NCBI Gene
Aliases
C1-INH, C1IN, C1INH, C1NH, HAE1, HAE2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P05155Plasma protease C1 inhibitor5005Ensembl, GeneID, HGNC

Source UniProt

Patents227

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21141P05155Espacenet
WO 2025262255 A12025-12-2650P05155Espacenet
EP 4650780 A22025-11-193018P05155Espacenet
JP 2025169942 A2025-11-141274P05155Espacenet
JP 2025147176 A2025-10-0612113P05155Espacenet
JP 2025529142 A2025-09-047692P05155Espacenet
US 12371689 B22025-07-297692P05155Espacenet
EP 4587839 A22025-07-232P05155Espacenet
EP 4582098 A22025-07-091401P05155Espacenet
JP 2025517970 A2025-06-123018P05155Espacenet

1 to 10 of 227

See all 227 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
CONESTAT ALFACHEMBL2108350Plasma protease C1 inhibitor exogenous proteinEXOGENOUS PROTEIN

Source ChEMBL

Trials23

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06679426CONESTAT ALFAPHASE3ClinicalTrials.gov
NCT06361537CONESTAT ALFAPHASE3ClinicalTrials.gov
NCT06359782CONESTAT ALFAPHASE2ClinicalTrials.gov
NCT03697187CONESTAT ALFAClinicalTrials.gov
NCT02134314CONESTAT ALFAPHASE1/PHASE22018-06-25ClinicalTrials.gov
NCT01766414CONESTAT ALFAPHASE3ClinicalTrials.gov
NCT01760343CONESTAT ALFAPHASE1ClinicalTrials.gov
NCT01759602CONESTAT ALFAPHASE12014-07-18ClinicalTrials.gov
NCT01576523CONESTAT ALFAPHASE1/PHASE22021-02-01ClinicalTrials.gov
NCT01467947CONESTAT ALFAPHASE42015-11-16ClinicalTrials.gov

1 to 10 of 23

See all 23 trials

NIH grants1,786

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA008748Cancer Center Support Grant92025
P30CA046934University of Colorado Cancer Center Support Grant72025
T32GM008315Mechanisms of Trauma-Induced Coagulopathy72025
UL1TR001863Yale Clinical and Translational Science Award72025
P30DK034854Integrated Epithelial and Muscosal Biology62025
ZIAAI001083Studies in the Pathogenesis of Systemic Capillary Leak Syndrome62025
P30DK036836Diabetes Research Center52025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success52025
UL1TR002345Washington University Institute of Clinical and Translational Sciences52025
R01CA200423Chemical Glycoproteomics42025

1 to 10 of 1,786Source NIH's project files

See all 1,786 nih grants

Papers4,575

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825908PubTator, text miningPubMed
42821175PubTator, text miningPubMed
42800013PubTator, text miningPubMed
42796242PubTator, text miningPubMed
42777333PubTator, text miningPubMed
42755627PubTator, text miningPubMed
42718639PubTator, text miningPubMed
42671775PubTator, text miningPubMed
42649349PubTator, text miningPubMed
42643423PubTator, text miningPubMed

1 to 10 of 4,575

See all 4,575 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/710

GET https://conductscience.org/api/genes/v1/710/patents?page=2