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Gene · 7114

TMSB4X: thymosin beta 4 X-linked

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TMSB4X: thymosin beta 4 X-linked. Genes, record 7114. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7114

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Gene

Symbol
TMSB4X
HGNC
Name
thymosin beta 4 X-linked
HGNC
NCBI Gene ID
7114
NCBI Gene
HGNC ID
HGNC:11881
HGNC
Ensembl
ENSG00000205542
NCBI Gene
Aliases
FX, PTMB4, TB4X, TMSB4
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P62328Thymosin beta-4443Ensembl, GeneID, HGNC

Source UniProt

Patents122

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467056P62328Espacenet
JP 2026004568 A2026-01-1467057P62328Espacenet
JP 2026004568 A2026-01-1467058P62328Espacenet
JP 2026004568 A2026-01-1467059P62328Espacenet
EP 4650780 A22025-11-1910344P62328Espacenet
EP 4641201 A22025-10-2910664P62328Espacenet
JP 2025517969 A2025-06-1210664P62328Espacenet
JP 2025517970 A2025-06-1210344P62328Espacenet
WO 2024226499 A12024-10-3126P62328Espacenet
EP 4373841 A12024-05-2952P62328Espacenet

1 to 10 of 122

See all 122 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,160

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTMSB4X papersNewest fiscal year
P30EY004068Core Grant for Vision Research102025
R01GM073791Structural-Functional Basis of Actin Cytoskeleton Dynamics62025
P30DA018310Neurometabolomics and Neuroproteomics Center on Cell-Cell Signaling52025
R01EY013431Mechanisms of epithelial alterations in diabetic cornea52025
R01HL076485Engineering Vascularized Cardiac Muscle42025
P30CA006973Regional Oncology Research Center32025
P30CA068485Cancer Center Support Grant32025
P30EY007551Center Core Grant for Vision Research32025
R01GM114666Molecular Mechanisms of Bacterial Toxins Targeting the Actin Cytoskeleton32025
R35GM133485Mechanisms of coordinated actin and microtubule dynamics32025

1 to 10 of 1,160Source NIH's project files

See all 1,160 nih grants

Papers2,131

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Craniofacial Involvement Is Associated With Poor Prognosis in Extranodal Diffuse Large B-Cell Lymphoma.Hematol Oncol202642781756PubTator, text miningPubMed
Recombinant human Thymosin β4 ameliorates experimental colitis and intestinal fibrosis through suppression of mineralocorticoid receptor signaling.Mol Biomed202642606759PubTator, text miningPubMed
Peptide Supplements and Their Therapeutic Applications in Sports Medicine.Am J Sports Med202642578445PubTator, text miningPubMed
[TMSB4X Promotes Proliferation and Metastasis of T-cell Acute Lymphoblastic Leukemia Cells by Regulating the Wnt/β-catenin Signaling Pathway].Zhongguo Shi Yan Xue Ye Xue Za Zhi202642544648PubTator, text miningPubMed
Urinary proteomic signature of exercise intolerance in patients at risk of heart failure: evidence from the HOMAGE trial.EBioMedicine202642531722PubTator, text miningPubMed
Spatial transcriptomic analysis reveals spatial features in human Stanford type A aortic dissection.iScience202642519065PubTator, text miningPubMed
Dysregulation of circulating damage-associated molecular patterns in diabetic foot syndrome.Front Immunol202642440461PubTator, text miningPubMed
PEGylated thymosin β4 is a thiol-site-specific prodrug treating myocardial infarction in vivo.Bioeng Transl Med202642394899PubTator, text miningPubMed
Sprayable bioadhesive microcarriers loaded with Tβ4-Engineered ADSC exosomes for diabetic wound healing.Bioact Mater202642383202PubTator, text miningPubMed
Longitudinal Trends of Salivary Oxidized Thymosin β4 and β10 in Preterm Infants with Bronchopulmonary Dysplasia.Children (Basel)202642353940PubTator, text miningPubMed

1 to 10 of 2,131

See all 2,131 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7114

GET https://conductscience.org/api/genes/v1/7114/patents?page=2