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CLDN5: claudin 5

1 protein, 40 patents, 0 drugs, 0 trials, 3,035 NIH grants and 5,379 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolCLDN5HGNC
Nameclaudin 5HGNC
NCBI Gene ID7122NCBI Gene
HGNC IDHGNC:2047HGNC
EnsemblENSG00000184113NCBI Gene
AliasesAWAL, BEC1, CPETRL1, TMDVCF, TMVCFNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O00501Claudin-52180Ensembl, GeneID, HGNCUniProt

Patents 40

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2025244006 A2025-11-271O00501Espacenet
JP 2025529142 A2025-09-04990O00501Espacenet
US 12371689 B22025-07-29990O00501Espacenet
JP 2024522861 A2024-06-2150O00501Espacenet
WO 2023195509 A2023-10-122O00501Espacenet
US 11446398 B22022-09-2017568O00501Espacenet
JP 2022524081 A2022-04-27120539O00501Espacenet
US 11053313 B22021-07-0627O00501Espacenet
US 10882906 B22021-01-0573O00501Espacenet
KR 1020200004810 A2020-01-1427O00501Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3035

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01MH072567HIV-1 and amyloid beta interactions at the blood-brain barrier202,025NIH's project files
P40OD010440Caenorhabditis Genetics Center122,025NIH's project files
UL1TR002378Georgia Clinical & Translational Science Alliance (Georgia CTSA)112,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)92,025NIH's project files
R01MH128022Defining brain pericytes as a novel and myeloid-derived HIV reservoir82,025NIH's project files
U54GM104942West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health82,025NIH's project files
P30CA016672Cancer Center Support Grant72,025NIH's project files
P30EY007003University of Michigan Vision Research Center62,025NIH's project files
R01MH104559ROLE OF PERIPHERAL IMMUNE-DERIVED MMP8 IN STRESS SUSCEPTIBILITY62,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award62,025NIH's project files

Papers 5379

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42819783PubTator, text miningPubMed
42819782PubTator, text miningPubMed
42808450PubTator, text miningPubMed
42804124PubTator, text miningPubMed
42800684PubTator, text miningPubMed
42797527PubTator, text miningPubMed
42778011PubTator, text miningPubMed
42730797PubTator, text miningPubMed
42722082PubTator, text miningPubMed
42718815PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license