ConductScience.org, home

Library / Genes

TNFAIP3: TNF alpha induced protein 3

1 protein, 93 patents, 0 drugs, 0 trials, 4,645 NIH grants and 8,064 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTNFAIP3HGNC
NameTNF alpha induced protein 3HGNC
NCBI Gene ID7128NCBI Gene
HGNC IDHGNC:11896HGNC
EnsemblENSG00000118503NCBI Gene
AliasesA20, AIFBL1, AISBL, OTUD7C, TNFA1P2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P21580Tumor necrosis factor alpha-induced protein 379017Ensembl, GeneID, HGNCUniProt

Patents 93

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026171886 A12026-08-209P21580Espacenet
JP 2026004568 A2026-01-1468686P21580Espacenet
JP 2026000906 A2026-01-06248P21580Espacenet
EP 4650780 A22025-11-19936P21580Espacenet
EP 4640849 A22025-10-29106P21580Espacenet
EP 4641201 A22025-10-29658P21580Espacenet
EP 4641202 A22025-10-294397P21580Espacenet
JP 2025524002 A2025-07-2513P21580Espacenet
JP 2025519096 A2025-06-24106P21580Espacenet
JP 2025517969 A2025-06-12658P21580Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4645

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant442,025NIH's project files
P30CA016672Cancer Center Support Grant302,025NIH's project files
P30DK026743UCSF Liver Center162,025NIH's project files
T32DK007007INRSA Training Grant in Gastroenterology152,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital142,025NIH's project files
R01AI024717Genetic Linkage in Lupus122,025NIH's project files
ZIAHG200372Genetics, Pathophysiology, and Treatment of Autoinflammatory and Autoimmune Diseases122,025NIH's project files
U54GM104938Oklahoma Shared Clinical and Translational Resources112,025NIH's project files
R01AI046712Activation of Macrophages in Human Autoimmune Diseases102,025NIH's project files
R01AR046713Cytokine regulation of RA synoviocyte phenotype102,025NIH's project files

Papers 8064

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42806754PubTator, text miningPubMed
42793037PubTator, text miningPubMed
42772990PubTator, text miningPubMed
42741419PubTator, text miningPubMed
42732930PubTator, text miningPubMed
42732763PubTator, text miningPubMed
42716213PubTator, text miningPubMed
42704536PubTator, text miningPubMed
42694747PubTator, text miningPubMed
42682521PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license