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Gene · 7130

TNFAIP6: TNF alpha induced protein 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TNFAIP6: TNF alpha induced protein 6. Genes, record 7130. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7130

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Gene

Symbol
TNFAIP6
HGNC
Name
TNF alpha induced protein 6
HGNC
NCBI Gene ID
7130
NCBI Gene
HGNC ID
HGNC:11898
HGNC
Ensembl
ENSG00000123610
NCBI Gene
Aliases
TSG-6, TSG6
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P98066Tumor necrosis factor-inducible gene 6 protein2775Ensembl, GeneID, HGNC

Source UniProt

Patents134

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468695P98066Espacenet
EP 4650780 A22025-11-191091P98066Espacenet
EP 4641201 A22025-10-29765P98066Espacenet
JP 2025147176 A2025-10-0613556P98066Espacenet
JP 2025529142 A2025-09-047934P98066Espacenet
KR 1020250129138 A2025-08-2910P98066Espacenet
US 12384828 B22025-08-1250P98066Espacenet
US 12371689 B22025-07-297934P98066Espacenet
JP 2025517969 A2025-06-12765P98066Espacenet
JP 2025517970 A2025-06-121091P98066Espacenet

1 to 10 of 134

See all 134 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,239

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTNFAIP6 papersNewest fiscal year
P30DK078392Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease82025
P30DK017047Diabetes Research Center62025
P30EY001792P30 Core Grant for Vision Research62025
U19AI070235Epithelial Genes in Allergic Inflammation62025
ZIAES102605The Role of Hyaluronan And Inter-Alpha-Trypsin Inhibitor in Tissue Injury62025
P30CA014520UW Comprehensive Cancer Center Support52025
P30CA068485Cancer Center Support Grant52025
P51OD011104Tulane National Primate Research Center52025
K12EY021475UIC K12 independent Clinical Vision Scientist Development Program42025
P30AG028716Duke Claude D. Pepper Older Americans Independence Center42025

1 to 10 of 1,239Source NIH's project files

See all 1,239 nih grants

Papers2,523

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Construction of an Esophageal Cancer Prognostic Model Based on Mitochondrial Energy Metabolism-Related Genes and Mechanism of INHBA in Promoting Malignant Progression via the Smad2/3 Pathway.Biomolecules202642793200PubTator, text miningPubMed
YAP1 Is Associated with Cumulus Expansion-Related Factor Expression and Autophagy-Related Signaling in Yak Cumulus Cells.Animals (Basel)202642738425PubTator, text miningPubMed
TNFAIP6, an independent prognostic monitor and therapy target, promoted low-grade glioma recurrence and progression via JAK3-STAT6 signaling.Int J Surg202642682290PubTator, text miningPubMed
Regulation of TMEM2-mediated hyaluronan degradation by CD44 and LYVE-1.Front Mol Biosci202642656528PubTator, text miningPubMed
Identification of Cellular Senescence-Related Hub Genes in Rheumatoid Arthritis from Bioinformatics Analysis Through Machine Learning up to Verifications in Mouse Macrophages and Tests in Patients.Int J Mol Sci202642653491PubTator, text miningPubMed
Single-cell transcriptomics reveals a correlation between inflammatory C7 fibroblasts in cervical tumor-adjacent normal tissues and cervical cancer progression.Front Cell Dev Biol202642638795PubTator, text miningPubMed
Multifaceted roles of CD44 in cancer progression and targeted therapeutic strategies.Exp Mol Med202642552379PubTator, text miningPubMed
Early morphological and gene/protein expression dynamics of human synovial mesenchymal stem cells during adhesion to a damaged meniscal surface.Sci Rep202642481601PubTator, text miningPubMed
TSG-6 protects orbital fibroblasts via anti-inflammation and anti-fibrosis effects in thyroid eye disease.Sci Rep202642399357PubTator, text miningPubMed
Genetic and molecular architecture of multiple sclerosis in gulf cooperation council populations: A scoping review and regional precision-neurology perspective.Mult Scler Relat Disord202642398277PubTator, text miningPubMed

1 to 10 of 2,523

See all 2,523 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7130

GET https://conductscience.org/api/genes/v1/7130/patents?page=2