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TNFRSF1A: TNF receptor superfamily member 1A

1 protein, 321 patents, 1 drug, 0 trials, 10,055 NIH grants and 21,050 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTNFRSF1AHGNC
NameTNF receptor superfamily member 1AHGNC
NCBI Gene ID7132NCBI Gene
HGNC IDHGNC:11916HGNC
EnsemblENSG00000067182NCBI Gene
AliasesCD120a, FPF, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, p55, p55-R, p60NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P19438Tumor necrosis factor receptor superfamily member 1A45515Ensembl, GeneID, HGNCUniProt

Patents 321

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11322P19438Espacenet
EP 4689072 A12026-02-11479P19438Espacenet
WO 2026019692 A22026-01-2217P19438Espacenet
JP 2025538460 A2025-11-2812P19438Espacenet
KR 1020250166188 A2025-11-27479P19438Espacenet
WO 2025240680 A12025-11-203P19438Espacenet
EP 4650780 A22025-11-19124P19438Espacenet
EP 4640849 A22025-10-2914P19438Espacenet
EP 4641201 A22025-10-29101P19438Espacenet
JP 2025163070 A2025-10-28393P19438Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
GSK-1995057CHEMBL2109590Tumor necrosis factor receptor R1 inhibitorINHIBITORChEMBL

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 10055

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant622,025NIH's project files
P30CA008748Cancer Center Support Grant302,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award292,025NIH's project files
P01CA039542Cellular and Molecular Studies of Bone Marrow Transplant242,025NIH's project files
P30CA047904Cancer Center Support Grant242,025NIH's project files
ZIDAR041180Clinical Support Services for the NIAMS Intramural Research Program212,025NIH's project files
P30DK036836Diabetes Research Center182,025NIH's project files
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital162,025NIH's project files
ZIAHG200372Genetics, Pathophysiology, and Treatment of Autoinflammatory and Autoimmune Diseases152,025NIH's project files
P30AI036219Rustbelt Center for AIDS Research (Case/UHC-Pitt CFAR)142,025NIH's project files

Papers 21050

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42819125PubTator, text miningPubMed
42818027PubTator, text miningPubMed
42807813PubTator, text miningPubMed
42796582PubTator, text miningPubMed
42794467PubTator, text miningPubMed
42786119PubTator, text miningPubMed
42782792PubTator, text miningPubMed
42762499PubTator, text miningPubMed
42759216PubTator, text miningPubMed
42743910PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license