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TP53BP1: tumor protein p53 binding protein 1

1 protein, 44 patents, 0 drugs, 0 trials, 5,461 NIH grants and 9,961 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTP53BP1HGNC
Nametumor protein p53 binding protein 1HGNC
NCBI Gene ID7158NCBI Gene
HGNC IDHGNC:11999HGNC
EnsemblENSG00000067369NCBI Gene
Aliases53BP1, TDRD30, p202, p53BP1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q12888TP53-binding protein 11,97245Ensembl, GeneID, HGNCUniProt

Patents 44

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-192256Q12888Espacenet
EP 4641201 A22025-10-291827Q12888Espacenet
JP 2025517969 A2025-06-121827Q12888Espacenet
JP 2025517970 A2025-06-122256Q12888Espacenet
EP 4464338 A22024-11-20283Q12888Espacenet
JP 2024123008 A2024-09-108892Q12888Espacenet
US 11680268 B22023-06-20283Q12888Espacenet
US 11446398 B22022-09-2094004Q12888Espacenet
JP 2022524081 A2022-04-27196975Q12888Espacenet
US 11261466 B22022-03-0112Q12888Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5461

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1082,025NIH's project files
P30CA008748Cancer Center Support Grant822,025NIH's project files
P01CA092584Structural Cell Biology of DNA Repair Machines452,025NIH's project files
ZIABC010283DNA repair352,025NIH's project files
ZIABC010959Relationship between DNA damage detection and signaling322,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program242,025NIH's project files
P30CA047904Cancer Center Support Grant242,025NIH's project files
ZIABC006150DNA Repair, Cell Cycle Checkpoints and Apoptosis as Targets for Anticancer Drugs232,025NIH's project files
P30CA142543UT Southwestern Medical Center Simmons Comprehensive Cancer Center222,025NIH's project files
P30CA016086Cancer Center Support Grant202,025NIH's project files

Papers 9961

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823448PubTator, text miningPubMed
42818163PubTator, text miningPubMed
42816477PubTator, text miningPubMed
42804094PubTator, text miningPubMed
42800164PubTator, text miningPubMed
42797330PubTator, text miningPubMed
42794664PubTator, text miningPubMed
42793752PubTator, text miningPubMed
42791328PubTator, text miningPubMed
42784603PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license