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TPH1: tryptophan hydroxylase 1
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Gene · 7166

Papers2,118

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,118

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TitleJournalYearPMIDFound bySource
Intestinal Epithelial-Protective Effects of Leuconostoc mesenteroides H40 in LPS-Stimulated HT-29 Cells.J Microbiol Biotechnol202642770193PubTator, text miningPubMed
Targeting tryptophan hydroxylase 1 restricts growth and suppresses plasticity in neuroendocrine prostate cancer.J Clin Invest202642752508PubTator, text miningPubMed
A pulmonary innate lymphoid cell-driven serotonergic neuroimmune axis orchestrates airway hyperreactivity and cough hypersensitivity.Immunity202642705228PubTator, text miningPubMed
Proteomic analysis reveals a metabolic switch and cellular remodelling in pancreatic-like cell spheroids cocultured with hepatocyte-like cells using an interconnected liver-pancreas-on-chip system.Mol Omics202642644453PubTator, text miningPubMed
Genetic evidence for a causal relationship between melatonin metabolism and depression.J Affect Disord202642532281PubTator, text miningPubMed
T peripheral helper 1 cells effectively drive atypical double-negative CD11chi B cells to antibody-secreting cells and play a pathogenic role in systemic lupus erythematosus.Clin Immunol202642447945PubTator, text miningPubMed
Astragaloside IV Alleviates DSS-Induced Ulcerative Colitis by Modulating Host-Gut Tryptophan Metabolism.Foods202642195848PubTator, text miningPubMed
Plasma Tryptophan Hydroxylase 1 Activity-related Metabolic Markers and Stroke Risk: A Nested Case-control Study.Transl Stroke Res202642033575PubTator, text miningPubMed
Anisotropic excipient-free buccal wafer engineered by directional freezing for structure-guided neuro-immune therapy against chemotherapy-induced emesis.Acta Biomater202642002060PubTator, text miningPubMed
Genotype-stratified Default Mode Network hyperconnectivity in major depressive disorder: an MR imaging genetics study.J Affect Disord202641956213PubTator, text miningPubMed
Integrative Analysis of Post-Translational Modifications Identifies a PTM-Enriched Regulatory Core in Human Metabolic Enzymes.Metabolites202641893314PubTator, text miningPubMed
Quantifying the fidelity of in vitro human cell culture systems using a biomedical foundation model.Proc Natl Acad Sci U S A202641860964PubTator, text miningPubMed
A Study of Candidate Genes Associated with Suicide Attempts in the Kazakh Population in Astana, Kazakhstan.Int J Mol Sci202641828514PubTator, text miningPubMed
Advances in intratumoral immunotherapy from a neuro-immune-endocrine perspective for breast cancer treatment.Front Oncol202641800053PubTator, text miningPubMed
Reviewing the Peripheral and Central Mechanisms of Visceral Hypersensitivity in Intestinal Disorders.Int J Med Sci202641799760PubTator, text miningPubMed
The impact of continuous positive airway pressure combined with lifestyle intervention on patients with obstructive sleep apnea: a multilevel meta-analysis.Front Med (Lausanne)202641797797PubTator, text miningPubMed
Metabolomic profiling in phenylketonuria: a systematic review of human studies.Metabolomics202641793569PubTator, text miningPubMed
Gut microbiota and bone aging: Focusing on the gut-X axis modes.J Orthop Translat202641777702PubTator, text miningPubMed
Biomarker-directed aptamer panels for diagnosis and differentiation of neuroendocrine tumors.J Neuroendocrinol202641761637PubTator, text miningPubMed
The Genetic Mosaic of Depression: Linking Polymorphisms to Neuroplasticity and Stress Regulation.Pharmaceuticals (Basel)202641754876PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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