Gene · 717
C2: complement C2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. C2: complement C2. Genes, record 717. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/717
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P06681 | Complement C2 | 752 | 14 | Ensembl, GeneID, HGNC |
Source UniProt
Patents119
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026515744 A | 2026-05-19 | 121 | P06681 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41983 | P06681 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41985 | P06681 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41987 | P06681 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41989 | P06681 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41993 | P06681 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 41997 | P06681 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 42022 | P06681 | Espacenet |
| WO 2025257157 A1 | 2025-12-18 | 1 | P06681 | Espacenet |
| WO 2025238225 A1 | 2025-11-20 | 1 | P06681 | Espacenet |
1 to 10 of 119
See all 119 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,292
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | C2 papers | Newest fiscal year |
|---|---|---|---|
| P30EY014800 | University of Utah Core Vision Research Grant | 7 | 2025 |
| K12EY016335 | Harvard-Vision Clinical Scientist Development Program | 6 | 2025 |
| P30EY014801 | Miami Center for Vision Research | 6 | 2025 |
| R01EY022445 | Use of Correlated Data Methods in Ophthalmology | 5 | 2025 |
| R01AI024717 | Genetic Linkage in Lupus | 4 | 2025 |
| I01RX000444 | Complement Factor H-based Therapeutic Strategies in Macular Degeneration | 3 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 3 | 2025 |
| K08AR081412 | Architecture and interactions of Granzyme K+ CD8 T cells in inflamed synovium in rheumatoid arthritis | 2 | 2025 |
| P01AI148102 | Differentiation of immune cells and fibrobalsts in inflamed tissue in RA and SLE | 2 | 2025 |
1 to 10 of 1,292Source NIH's project files
See all 1,292 nih grantsPapers2,431
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Cobalt-mediated suppression of IFN-γ-JAK-STAT1 signaling reprograms IDO1-driven immunosuppression for metalloimmunotherapy. | Sci Adv | 2026 | 42758828 | PubTator, text mining | PubMed |
| Plasma protein profile in patients with antiphospholipid syndrome and controls without antiphospholipid syndrome. | J Thromb Haemost | 2026 | 42674367 | PubTator, text mining | PubMed |
| Systematic review of extracellular vesicle-based liquid biopsy for leptomeningeal metastasis: current evidence and future directions. | Clin Exp Metastasis | 2026 | 42484930 | PubTator, text mining | PubMed |
| Apnea Testing for Brain Death/Death by Neurologic Criteria in Adults: A Prospective Multicenter Observational Study Assessing the Relationship Between Methodology, Safety, and Duration. | Crit Care Explor | 2026 | 42390295 | PubTator, text mining | PubMed |
| Investigation of metal identity on the structure and electronic properties of dinuclear Mn and Co complexes with triaryl tetradentate ligands. | Dalton Trans | 2026 | 42300565 | PubTator, text mining | PubMed |
| Ultra-hydrophilic MXene nanoplatform unraveling plasma N-glycopeptide in epidural-related maternal fever. | Mikrochim Acta | 2026 | 42277438 | PubTator, text mining | PubMed |
| Aptamers with magnetically tunable affinity for divalent cobalt ions. | Nat Commun | 2026 | 41851151 | PubTator, text mining | PubMed |
| CSL305: A Dual Functional Therapeutic Antibody Targeting Complement C2 and FcRn. | Int J Mol Sci | 2026 | 41828601 | PubTator, text mining | PubMed |
| Iron, arginine, and redox metabolism in peripheral blood mononuclear cells distinguishes sickle cell disease and pulmonary hypertension. | Hemasphere | 2026 | 41799249 | PubTator, text mining | PubMed |
| The mitogenome mutation repertoire affects progression of Parkinson's Disease. | Genet Mol Biol | 2026 | 41790955 | PubTator, text mining | PubMed |
1 to 10 of 2,431
See all 2,431 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/717
GET https://conductscience.org/api/genes/v1/717/patents?page=2