ConductScience.org, home

Library / Genes

HSP90B1: heat shock protein 90 beta family member 1

1 protein, 163 patents, 0 drugs, 0 trials, 3,330 NIH grants and 5,776 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolHSP90B1HGNC
Nameheat shock protein 90 beta family member 1HGNC
NCBI Gene ID7184NCBI Gene
HGNC IDHGNC:12028HGNC
EnsemblENSG00000166598NCBI Gene
AliasesECGP, GP96, GRP94, HEL-S-125m, HEL35, TRA1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P14625Endoplasmin8034Ensembl, GeneID, HGNCUniProt

Patents 163

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-193965P14625Espacenet
EP 4641201 A22025-10-293539P14625Espacenet
JP 2025147176 A2025-10-066603P14625Espacenet
EP 4619546 A12025-09-244P14625Espacenet
JP 2025529142 A2025-09-046619P14625Espacenet
US 12371689 B22025-07-296619P14625Espacenet
EP 4582098 A22025-07-091366P14625Espacenet
JP 2025517969 A2025-06-123539P14625Espacenet
JP 2025517970 A2025-06-123965P14625Espacenet
JP 2025028160 A2025-02-286603P14625Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3330

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant352,025NIH's project files
P30CA016672Cancer Center Support Grant192,025NIH's project files
P30CA138313Medical University of South Carolina - Cancer Center Support Grant142,025NIH's project files
ZIASC010074HSP90 and HSP70 Chaperone Proteins and Interactors in Cellular Signal Transduction142,025NIH's project files
R01EY021205Characterization of purified myocilin: glaucoma as a protein misfolding disease122,025NIH's project files
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)92,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)92,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant82,025NIH's project files
P30DK034854Integrated Epithelial and Muscosal Biology82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files

Papers 5776

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42793153PubTator, text miningPubMed
42776300PubTator, text miningPubMed
42749233PubTator, text miningPubMed
42734641PubTator, text miningPubMed
42731610PubTator, text miningPubMed
42677072PubTator, text miningPubMed
42653403PubTator, text miningPubMed
42612061PubTator, text miningPubMed
42587007PubTator, text miningPubMed
42583687PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license