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TRAF2: TNF receptor associated factor 2

1 protein, 64 patents, 0 drugs, 0 trials, 3,892 NIH grants and 6,975 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTRAF2HGNC
NameTNF receptor associated factor 2HGNC
NCBI Gene ID7186NCBI Gene
HGNC IDHGNC:12032HGNC
EnsemblENSG00000127191NCBI Gene
AliasesMGC:45012, RNF117, TRAP, TRAP3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q12933TNF receptor-associated factor 250115Ensembl, GeneID, HGNCUniProt

Patents 64

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12539325 B22026-02-0360Q12933Espacenet
EP 4650780 A22025-11-191227Q12933Espacenet
EP 4641201 A22025-10-29871Q12933Espacenet
JP 2025147176 A2025-10-0616541Q12933Espacenet
JP 2025517969 A2025-06-12871Q12933Espacenet
JP 2025517970 A2025-06-121227Q12933Espacenet
JP 2025028160 A2025-02-2816541Q12933Espacenet
KR 1020250010750 A2025-01-2116541Q12933Espacenet
US 12133879 B22024-11-0560Q12933Espacenet
JP 2024123008 A2024-09-108712Q12933Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3892

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant412,025NIH's project files
ZIASC010376TNF Signaling, Cell Death and Cancer152,025NIH's project files
P30CA008748Cancer Center Support Grant142,025NIH's project files
P01CA019014Viral Oncogenesis, Latency, and Replication122,025NIH's project files
P30CA086862Cancer Center Support Grant112,025NIH's project files
P30ES005605Environmental Health Sciences Research Center112,025NIH's project files
P30CA072720Cancer Center Support Grant102,025NIH's project files
P30CA016059Massey Cancer Center - Cancer Center Support Grant92,025NIH's project files
P30CA030199Cancer Center Support Grant (CCSG)82,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202882,025NIH's project files

Papers 6975

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42805065PubTator, text miningPubMed
42737621PubTator, text miningPubMed
42695863PubTator, text miningPubMed
42691731PubTator, text miningPubMed
42686832PubTator, text miningPubMed
42644246PubTator, text miningPubMed
42632295PubTator, text miningPubMed
42593841PubTator, text miningPubMed
42580648PubTator, text miningPubMed
42549838PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license