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TRAF6: TNF receptor associated factor 6

1 protein, 75 patents, 0 drugs, 0 trials, 5,108 NIH grants and 10,558 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolTRAF6HGNC
NameTNF receptor associated factor 6HGNC
NCBI Gene ID7189NCBI Gene
HGNC IDHGNC:12036HGNC
EnsemblENSG00000175104NCBI Gene
AliasesMGC:3310, RNF85NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q9Y4K3TNF receptor-associated factor 652213Ensembl, GeneID, HGNCUniProt

Patents 75

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1467192Q9Y4K3Espacenet
JP 2026004568 A2026-01-1467193Q9Y4K3Espacenet
EP 4650780 A22025-11-196313Q9Y4K3Espacenet
JP 2025524002 A2025-07-2522Q9Y4K3Espacenet
JP 2025102799 A2025-07-0857Q9Y4K3Espacenet
JP 2025517970 A2025-06-126313Q9Y4K3Espacenet
KR 1020250039465 A2025-03-2022Q9Y4K3Espacenet
JP 2025020284 A2025-02-1254Q9Y4K3Espacenet
JP 2024023699 A2024-02-2122Q9Y4K3Espacenet
JP 2024505890 A2024-02-0822Q9Y4K3Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5108

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant462,025NIH's project files
P30CA008748Cancer Center Support Grant192,025NIH's project files
P30DK034854Integrated Epithelial and Muscosal Biology132,025NIH's project files
P30CA016086Cancer Center Support Grant92,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)92,025NIH's project files
P01CA019014Viral Oncogenesis, Latency, and Replication82,025NIH's project files
R01AR062173The IL-23/IL-17 Axis in Inflammatory Arthritis82,025NIH's project files
T32AI089474Immunology Training Program-Predoctoral82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award82,025NIH's project files
P30CA030199Cancer Center Support Grant (CCSG)72,025NIH's project files

Papers 10558

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42793128PubTator, text miningPubMed
42778685PubTator, text miningPubMed
42758243PubTator, text miningPubMed
42744106PubTator, text miningPubMed
42730698PubTator, text miningPubMed
42719581PubTator, text miningPubMed
42713552PubTator, text miningPubMed
42705025PubTator, text miningPubMed
42698578PubTator, text miningPubMed
42678998PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license