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C4A: complement C4A (Chido/Rodgers blood group)

1 protein, 46 patents, 0 drugs, 0 trials, 2,611 NIH grants and 5,346 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolC4AHGNC
Namecomplement C4A (Chido/Rodgers blood group)HGNC
NCBI Gene ID720NCBI Gene
HGNC IDHGNC:1323HGNC
EnsemblENSG00000244731NCBI Gene
AliasesC4, C4A2, C4A3, C4A4, C4A6, C4AD, C4B, C4S, CO4, CPAMD2, RGNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P0C0L4Complement C4-A1,74412Ensembl, GeneID, HGNCUniProt

Patents 46

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12560619 B22026-02-24112P0C0L4Espacenet
JP 2026004568 A2026-01-1442071P0C0L4Espacenet
EP 4650780 A22025-11-1912801P0C0L4Espacenet
JP 2025147176 A2025-10-061899P0C0L4Espacenet
JP 2025529142 A2025-09-045685P0C0L4Espacenet
WO 2025165658 A12025-08-0739P0C0L4Espacenet
US 12371689 B22025-07-295685P0C0L4Espacenet
JP 2025517970 A2025-06-1212801P0C0L4Espacenet
US 12287342 B22025-04-2911P0C0L4Espacenet
JP 2025028160 A2025-02-281899P0C0L4Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2611

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition112,025NIH's project files
R01DK076690Complement-mediated injury of the kidney: New mechanisms and novel therapies102,025NIH's project files
R01AI024717Genetic Linkage in Lupus92,025NIH's project files
P30CA008748Cancer Center Support Grant72,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award62,025NIH's project files
R01AR051749Complement in the Pathogenesis of Autoimmune Arthritis52,025NIH's project files
R01DK078244Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes52,025NIH's project files
R01DK110023C3 Glomerulopathy -- A Collaborative Study52,025NIH's project files
R35CA197583Dissecting and Targeting Deregulated Mitochondrial Apoptosis in Human Cancer52,025NIH's project files
R50CA211399Stapled Peptides for Protein Interaction Research and Therapeutic Targeting in Human Cancer52,025NIH's project files

Papers 5346

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42817153PubTator, text miningPubMed
42781881PubTator, text miningPubMed
42748139PubTator, text miningPubMed
42741480PubTator, text miningPubMed
42737971PubTator, text miningPubMed
42731906PubTator, text miningPubMed
42700302PubTator, text miningPubMed
42662675PubTator, text miningPubMed
42615359PubTator, text miningPubMed
42508023PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license