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C4B: complement C4B (Chido/Rodgers blood group)

2 proteins, 92 patents, 0 drugs, 0 trials, 3,302 NIH grants and 6,183 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolC4BHGNC
Namecomplement C4B (Chido/Rodgers blood group)HGNC
NCBI Gene ID721NCBI Gene
HGNC IDHGNC:1324HGNC
EnsemblENSG00000224389NCBI Gene
AliasesC4B1, C4B12, C4B3, C4B5, C4BD, C4F, CH, CO4, CPAMD3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 2

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P0C0L4Complement C4-A1,74412GeneIDUniProt
P0C0L5Complement C4-B1,7444Ensembl, GeneID, HGNCUniProt

Patents 92

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12560619 B22026-02-24112P0C0L4Espacenet
JP 2026004568 A2026-01-1442071P0C0L4Espacenet
JP 2026004568 A2026-01-1442080P0C0L5Espacenet
JP 2026004568 A2026-01-1442082P0C0L5Espacenet
EP 4650780 A22025-11-1912801P0C0L4Espacenet
EP 4650780 A22025-11-1913979P0C0L5Espacenet
JP 2025147176 A2025-10-061899P0C0L4Espacenet
JP 2025147176 A2025-10-061902P0C0L5Espacenet
JP 2025529142 A2025-09-045685P0C0L4Espacenet
JP 2025529142 A2025-09-045686P0C0L5Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3302

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
U24AG021886National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)122,025NIH's project files
R01DK076690Complement-mediated injury of the kidney: New mechanisms and novel therapies92,025NIH's project files
R01DK110023C3 Glomerulopathy -- A Collaborative Study92,025NIH's project files
T32AR007279Immunobiology of the Rheumatic Diseases82,025NIH's project files
ZIAHL006223The role of the intracellular complement system - the complosome - in Th1 biology82,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant72,025NIH's project files
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions62,025NIH's project files
P01AG026276Antecedent Biomarkers for Alzheimer Disease: The Adult Children Study62,025NIH's project files
P30CA008748Cancer Center Support Grant62,025NIH's project files
R01AI024717Genetic Linkage in Lupus52,025NIH's project files

Papers 6183

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42748139PubTator, text miningPubMed
42700302PubTator, text miningPubMed
42662675PubTator, text miningPubMed
42584967PubTator, text miningPubMed
42553536PubTator, text miningPubMed
42538969PubTator, text miningPubMed
42477892PubTator, text miningPubMed
42477211PubTator, text miningPubMed
42472420PubTator, text miningPubMed
42461968PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license