Gene · 7222
TRPC3: transient receptor potential cation channel subfamily C member 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TRPC3: transient receptor potential cation channel subfamily C member 3. Genes, record 7222. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7222
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q13507 | Short transient receptor potential channel 3 | 921 | 19 | Ensembl, GeneID, HGNC |
Source UniProt
Patents15
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4641201 A2 | 2025-10-29 | 10496 | Q13507 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10496 | Q13507 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 37715 | Q13507 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 37715 | Q13507 | Espacenet |
| US 11723347 B2 | 2023-08-15 | 1 | Q13507 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 37715 | Q13507 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 90284 | Q13507 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 1434 | Q13507 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 193255 | Q13507 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 12027 | Q13507 | Espacenet |
1 to 10 of 15
See all 15 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,169
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TRPC3 papers | Newest fiscal year |
|---|---|---|---|
| ZIADE000438 | Molecular Mechanisms Regulating Calcium Flux In Salivary Glands | 21 | 2025 |
| R01DE017102 | TRPC1, Calcium, and Saliva Secretion | 17 | 2025 |
| R01HL056470 | Neonatal Modulation of Airway Contractility | 9 | 2025 |
| ZIADE000735 | Ca2+ signaling and HCO3- secretion by exocrine glands | 5 | 2025 |
| P30EY014800 | University of Utah Core Vision Research Grant | 4 | 2025 |
| R01CA206573 | Structure and function of Transient Receptor Potential Channels | 4 | 2025 |
| R01EY027920 | Molecular mechanisms of mechanotransduction in the aqueous outflow pathway | 4 | 2025 |
| R01HL131517 | Sex-specific arrhythmogenic mechanisms of atrial fibrillation | 4 | 2025 |
| R01NS100947 | Inflammatory regulation of epileptogenesis after status epilepticus | 4 | 2025 |
| P20GM113123 | Center for Excellence in Host Pathogen Interactions | 3 | 2025 |
1 to 10 of 1,169Source NIH's project files
See all 1,169 nih grantsPapers1,900
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Magnetic Mitohormesis as a Potential Non-Invasive Restorative Therapy for X-Linked Muscular Dystrophies. | Int J Mol Sci | 2026 | 42737597 | PubTator, text mining | PubMed |
| TRPC3-Driven Calcium Microdomains Instruct Peripheral Nerve Regeneration With Protective Implications for Central Neurons. | Adv Sci (Weinh) | 2026 | 42640085 | PubTator, text mining | PubMed |
| TRP matters: a pilot study on expression of mRNA in the parotid glands and their benign tumors. | Biochem Biophys Rep | 2026 | 42437085 | PubTator, text mining | PubMed |
| Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus. | Brain Pathol | 2026 | 42373097 | PubTator, text mining | PubMed |
| A new photochromic sterol controls TRPC3 activity by actuating a hub of regulatory lipid coordination. | Eur J Cell Biol | 2026 | 42284743 | PubTator, text mining | PubMed |
| The non-selective cation channels TRPC3 and TRPC6 in the human carotid body in the elderly. | Tissue Cell | 2026 | 42105474 | PubTator, text mining | PubMed |
| The role of IP3R and TRPC3 channels in vasoconstriction and hypertension. | Pflugers Arch | 2026 | 42068376 | PubTator, text mining | PubMed |
| Functional and structural basis of a hypermorphic TRPC3 variant. | Sci Adv | 2026 | 41880503 | PubTator, text mining | PubMed |
| TrpC5 silencing reduces cell invasion and migration and enhances radiosensitivity in papillary thyroid carcinoma cells. | Front Cell Dev Biol | 2026 | 41768995 | PubTator, text mining | PubMed |
| Lipid Regulation of Mechanosensitive Ion Channels. | Int J Mol Sci | 2026 | 41752117 | PubTator, text mining | PubMed |
1 to 10 of 1,900
See all 1,900 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7222
GET https://conductscience.org/api/genes/v1/7222/patents