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TRPC5: transient receptor potential cation channel subfamily C member 5
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Gene · 7224

Papers1,386

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,386

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TitleJournalYearPMIDFound bySource
Targeting the Medial Prefrontal Cortex with Transcranial Focused Ultrasound Alleviates Adolescent Sleep-Deprivation-Induced Persistent Postsurgical Pain in Adulthood.Research (Wash D C)202642781091PubTator, text miningPubMed
TRPC5 as a modulator of TRPV1 signalling in pathological pain states.Neuropharmacology202642385945PubTator, text miningPubMed
Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus.Brain Pathol202642373097PubTator, text miningPubMed
Baroreceptor Mechanotransduction: Diverse Sensors, Unified Signals.Hypertension202642261674PubTator, text miningPubMed
Transient Receptor Potential (TRP) channels: Quantitative biophysical correlates of cognitive function across brain regions.Behav Brain Res202642173407PubTator, text miningPubMed
(-)-Englerin A binding to human TRPC5 exposes an aromatic interaction network in channel activation.Nat Commun202642056091PubTator, text miningPubMed
Reactive oxygen species (ROS) in cancer: from mechanism to therapeutic implications.Signal Transduct Target Ther202641881983PubTator, text miningPubMed
ICAM-1 targeted extracellular vesicles loaded with HC-070 mitigate vascular oxidative stress and inflammation in obstructive sleep apnea hypopnea syndrome by inhibiting TRPC5.Free Radic Biol Med202641833586PubTator, text miningPubMed
Molecular hydrogen triggers TRPC4-TRPC4AP-dependent reversible calcium transients via extracellular influx.Theranostics202641799190PubTator, text miningPubMed
Cold exposure and human metabolism: A heterogeneous response across tissues and organs.Temperature (Austin)202641797814PubTator, text miningPubMed
TrpC5 silencing reduces cell invasion and migration and enhances radiosensitivity in papillary thyroid carcinoma cells.Front Cell Dev Biol202641768995PubTator, text miningPubMed
TRPC Channels as Mediators of Hypoxia-Induced Pulmonary Hypertension in Obstructive Sleep Apnea.Int J Mol Sci202641751997PubTator, text miningPubMed
Quantum Information Flow in Microtubule Tryptophan Networks.Entropy (Basel)202641751706PubTator, text miningPubMed
Progress of Research on the Metabolic Regulation of Lactylation in Muscle Tissues and Its Disease Associations.Biomolecules202641750282PubTator, text miningPubMed
Progress in the study of ion channel function, mechanisms, and mathematical modeling in Parkinson's disease.iScience202641732483PubTator, text miningPubMed
ATP release mediated by TRPM3 enhances invasion in glioblastoma.Anim Cells Syst (Seoul)202641710303PubTator, text miningPubMed
TRPV2 and TRPC5 are potential targets for astringent phytochemicals.Curr Res Food Sci202641586439PubTator, text miningPubMed
Structure-guided design of picomolar-level macrocyclic TRPC5 channel inhibitors with antidepressant activity.Acta Pharm Sin B202641584354PubTator, text miningPubMed
Ideal efficacy photoswitching for chromocontrol of TRPC4/5 channel functions in live tissues.Nat Chem Biol202641545580PubTator, text miningPubMed
Central control of gastrointestinal functions in health and disease.Physiol Rev202641432726PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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