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TRPM2: transient receptor potential cation channel subfamily M member 2
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Gene · 7226

Papers2,111

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,111

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TitleJournalYearPMIDFound bySource
Ginkgolide B Attenuates 6-Hydroxydopamine-Induced Cellular Damage and Modulates Oxidant-Evoked Ca2+ Signalling in SH-SY5Y Cells.Curr Issues Mol Biol202642793302PubTator, text miningPubMed
Brain-derived neurotrophic factor via TRPM2 inhibition reduces amyloid-beta-mediated increases of apoptosis and mitochondrial oxidative neurotoxicity in neuronal cells.Metab Brain Dis202642720842PubTator, text miningPubMed
Planned Ethanol Consumption in Pregnancy: Impact on Offspring Cardiac Autophagic Pathway via TRPM2 Channels-Implications for Fetal Alcohol Syndrome-Linked Cardiological Disorders.J Appl Toxicol202642656179PubTator, text miningPubMed
Psalmotoxin-1, a novel TRPM2 channel antagonist, reduces age-related macular degeneration-caused mitochondrial oxidative damage and apoptosis in human retinal pigment epithelial (ARPE-19) cells.Graefes Arch Clin Exp Ophthalmol202642560501PubTator, text miningPubMed
Neuroinflammation- molecular target based therapeutic approach.Adv Protein Chem Struct Biol202642448410PubTator, text miningPubMed
TRPM2 Deficiency Attenuates Allergic Rhinitis-Like Inflammation With Altered Ca2+-NFAT Signaling, Treg Responses, and sIgE Production.Immun Inflamm Dis202642438241PubTator, text miningPubMed
Integrative single-cell and multi-omics analysis of ZBTB21-mediated serine metabolism in colorectal cancer: from metabolic reprogramming to immune microenvironment modulation.Cancer Immunol Immunother202642400616PubTator, text miningPubMed
Sinapic Acid Reduces Hypoxia-Induced Cell Damage in Hep-2 Cells by Regulating TRPM2 Channel Activation.J Biochem Mol Toxicol202642345509PubTator, text miningPubMed
Liver-brain axis mechanism underlying central immune remodeling triggered by peripheral hepatic damage.Cell Signal202642242572PubTator, text miningPubMed
Corrigendum to " Knockdown of TRPM2 promotes osteogenic differentiation of Human Periodontal Ligament Stem Cells by modulating NF-κB /NLRP3 pathway", Tissue Cell, 2023, 84: 102184.Tissue Cell202642236400PubTator, text miningPubMed
Protective effects of zingerone against bisphenol-A induced oxidative stress and apoptosis in SH-SY5Y cells: the role of TRPM2 channel.Mol Biol Rep202642234058PubTator, text miningPubMed
Transient Receptor Potential (TRP) channels: Quantitative biophysical correlates of cognitive function across brain regions.Behav Brain Res202642173407PubTator, text miningPubMed
Correction: Protective role of zingerone against high glucose-Induced retinal pigment epithelial cell damage through modulation of the TRPM2 channel pathway.Mol Biol Rep202642165868PubTator, text miningPubMed
KCa3.1 mediates radioresistance of silver nanoparticles in human glioblastoma cells.Pflugers Arch202642156577PubTator, text miningPubMed
Thermosensitive TRP channels as dietary modulators of adipose thermogenesis: Implications for energy homeostasis and obesity.J Therm Biol202642102493PubTator, text miningPubMed
Ca2+ trapping by allosteric coupling explains species differences in TRPM2 inactivation reversibility.Commun Biol202642098306PubTator, text miningPubMed
Protein expression profiling of lenvatinib-resistant liver cancer cells and identify B4GALT4 as a critical drug resistance molecule.Discov Oncol202642091754PubTator, text miningPubMed
Blood-Based Epigenetic Signatures in Brazilian Males With Alcohol Use Disorder.Addict Biol202642047220PubTator, text miningPubMed
Correction: TRPM2: a pivotal player in tumor progression and a promising therapeutic target.Cancer Cell Int202642021243PubTator, text miningPubMed
Inhibiting the transient receptor potential melastatin 2 channel in microglia: current evidence and therapeutic potential in neurological disorders.Acta Pharmacol Sin202642020790PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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