TTN: titin

1 protein, 4 patents, 0 drugs, 0 trials, 4,473 NIH grants and 11,576 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Field	Value	Source
Symbol	TTN	HGNC
Name	titin	HGNC
NCBI Gene ID	7273	NCBI Gene
HGNC ID	HGNC:12403	HGNC
Ensembl	ENSG00000155657	NCBI Gene
Aliases	CMD1G, CMH9, CMPD4, CMYO5, CMYP5, EOMFC, FLJ32040, HMERF, LGMD2J, LGMDR10, MYLK5, SALMY, TMD	NCBI Gene
Type	protein-coding	NCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entry	Protein	Length	Structures	Gene stated in	Source
Q8WZ42	Titin	34,350	64	Ensembl, GeneID, HGNC	UniProt

Patents 4

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

Publication	Published	SEQ ID NO	Protein	Source
EP 4631537 A1	2025-10-15	1	Q8WZ42	Espacenet
JP 2023551068 A	2023-12-06	235	Q8WZ42	Espacenet
US 8741556 B2	2014-06-03	219	Q8WZ42	Espacenet
WO 2014049282 A1	2014-04-03	1	Q8WZ42	Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

Drug	ChEMBL ID	Mechanism	Action	Source

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

Trial	Drug	Phase	Results first posted	Source

NIH grants 4473

NIH projects whose papers are about the gene, through NIH's grant-paper links.

Project	Title	Its papers about the gene	Newest fiscal year	Source
P30CA008748	Cancer Center Support Grant	19	2,025	NIH's project files
R01HL092577	IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL	19	2,025	NIH's project files
R01HL105826	Fast myosin binding protein-C and cardiac contractility in heart failure	19	2,025	NIH's project files
UL1TR001863	Yale Clinical and Translational Science Award	16	2,025	NIH's project files
ZIANS003129	Molecular and Clinical Manifestations of Matrix and Aggregate Myopathies	16	2,025	NIH's project files
P20GM103432	Wyoming IDeA Networks for Biomedical Research Excellence Phase 4	15	2,025	NIH's project files
T32HL007249	Interdisciplinary Training in Cardiovascular Research	15	2,025	NIH's project files
P30CA016672	Cancer Center Support Grant	14	2,025	NIH's project files
P30GM138395	The Biophysics Collaborative Access Team	14	2,025	NIH's project files
R35HL144998	Role of the giant protein titin in cardiac health and disease	13	2,025	NIH's project files

Papers 11576

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMID	Found by	Source
42826309	PubTator, text mining	PubMed
42810719	PubTator, text mining	PubMed
42804542	PubTator, text mining	PubMed
42803950	PubTator, text mining	PubMed
42800472	PubTator, text mining	PubMed
42789100	PubTator, text mining	PubMed
42784204	PubTator, text mining	PubMed
42768780	PubTator, text mining	PubMed
42765307	PubTator, text mining	PubMed
42761362	PubTator, text mining	PubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license