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Gene · 7278

TUBA3C: tubulin alpha 3c

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TUBA3C: tubulin alpha 3c. Genes, record 7278. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7278

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Gene

Symbol
TUBA3C
HGNC
Name
tubulin alpha 3c
HGNC
NCBI Gene ID
7278
NCBI Gene
HGNC ID
HGNC:12408
HGNC
Ensembl
ENSG00000198033
NCBI Gene
Aliases
TUBA2, bA408E5.3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins2

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P0DPH7Tubulin alpha-3C chain4500Ensembl, GeneID, HGNCUniProt
P0DPH8Tubulin alpha-3D chain4500EnsemblUniProt

Patents78

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-2912372P0DPH7Espacenet
EP 4641201 A22025-10-2912372P0DPH8Espacenet
JP 2025517969 A2025-06-1212372P0DPH7Espacenet
JP 2025517969 A2025-06-1212372P0DPH8Espacenet
US 11564998 B22023-01-315432P0DPH7Espacenet
US 11564998 B22023-01-315432P0DPH8Espacenet
US 11564998 B22023-01-317066P0DPH7Espacenet
US 11564998 B22023-01-317066P0DPH8Espacenet
US 11446398 B22022-09-2093557P0DPH7Espacenet
US 11446398 B22022-09-2093557P0DPH8Espacenet

1 to 10 of 78

See all 78 patents

Drugs90

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AGS-16C3FCHEMBL4594455Tubulin disrupting agentDISRUPTING AGENTChEMBL
ANETUMAB RAVTANSINECHEMBL2109629Tubulin inhibitorINHIBITORChEMBL
ANG1005CHEMBL1089636Tubulin inhibitorINHIBITORChEMBL
ANVATABART OPADOTINCHEMBL4297892Tubulin inhibitorINHIBITORChEMBL
APRUTUMAB IXADOTINCHEMBL4650293Tubulin inhibitorINHIBITORChEMBL
ASG-5MECHEMBL2109574Tubulin inhibitorINHIBITORChEMBL
AVE-9633CHEMBL2109266Tubulin inhibitorINHIBITORChEMBL
AZINTUXIZUMAB VEDOTINCHEMBL4297859Tubulin inhibitorINHIBITORChEMBL
BELANTAMAB MAFODOTINCHEMBL4298209Tubulin inhibitorINHIBITORChEMBL
BIIB-015CHEMBL2109575Tubulin inhibitorINHIBITORChEMBL

1 to 10 of 90

See all 90 drugs

Trials8,728

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07604766PACLITAXELPHASE3ClinicalTrials.gov
NCT07602907PACLITAXELPHASE2ClinicalTrials.gov
NCT07601737PACLITAXELPHASE2ClinicalTrials.gov
NCT07601178PACLITAXELPHASE2ClinicalTrials.gov
NCT07599163PACLITAXELClinicalTrials.gov
NCT07595770PACLITAXELPHASE2ClinicalTrials.gov
NCT07594548PACLITAXELPHASE1ClinicalTrials.gov
NCT07591467DOCETAXELPHASE3ClinicalTrials.gov
NCT07589972VINORELBINEClinicalTrials.gov
NCT07588698VINCRISTINE SULFATEPHASE2ClinicalTrials.gov

1 to 10 of 8,728

See all 8,728 trials

NIH grants181

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTUBA3C papersNewest fiscal year
P30CA008748Cancer Center Support Grant22025
P30CA016672Cancer Center Support Grant22025
P30CA054174Mays Cancer Center at UT Health SA22025
P50HD096723Genetics of Male Infertility: Accelerating the pace of discovery22025
R01HD078641Genomics of spermatogenic impairment22025
K12GM093854IRACDA at Rutgers: INSPIRE Postdoctoral Training Program12025
K12HD000850Pediatric Scientist Development Program12025
P30CA062203Cancer Center Support Grant12025
P30CA069533OHSU Knight Cancer Institute12025
P30DK020572Michigan Diabetes Research Center (MDRC)12025

1 to 10 of 181Source NIH's project files

See all 181 nih grants

Papers236

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Reversing Mitochondrial Dysfunction in Optineurin E50K Glaucoma: A Metabolic Approach to Neuroprotection.Res Sq202641756461PubTator, text miningPubMed
Multiomics approaches in Kawasaki disease: insights into pathogenesis and emerging directions for diagnosis and treatment.Clin Exp Pediatr202641736230PubTator, text miningPubMed
Genome-wide association study of corneal dystrophy uncovers novel risk loci and enables improved polygenic prediction of Fuchs endothelial corneal dystrophy.medRxiv202641728327PubTator, text miningPubMed
Planarian microtubules form a network within muscle and regulate injury-induced genes essential for regeneration patterning.Development202541099309PubTator, text miningPubMed
Machine learning-based identification of diagnostic and prognostic mitotic cell cycle genes in hepatocellular carcinoma.PLoS One202540875626PubTator, text miningPubMed
Glucosylsphingosine affects mitochondrial function in a neuronal cell model.Commun Biol202540841705PubTator, text miningPubMed
Age-Associated Proteomic Changes in Human Spermatozoa.Int J Mol Sci202540649876PubTator, text miningPubMed
Identification of Novel Biomarkers Related to Vesicle Trafficking in Alzheimer's Disease Using Bioinformatics Approaches.Neurochem Res202540338387PubTator, text miningPubMed
Genome sequencing of Pakistani families with male infertility identifies deleterious genotypes in SPAG6, CCDC9, TKTL1, TUBA3C, and M1AP.Andrology202538073178PubTator, text miningPubMed
The Rogdi knockout mouse is a model for Kohlschütter-Tönz syndrome.Sci Rep202438172607PubTator, text miningPubMed

1 to 10 of 236

See all 236 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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