ConductScience.org, home

Gene · 7280

TUBB2A: tubulin beta 2A class IIa

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. TUBB2A: tubulin beta 2A class IIa. Genes, record 7280. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7280

On this page

Gene

Symbol
TUBB2A
HGNC
Name
tubulin beta 2A class IIa
HGNC
NCBI Gene ID
7280
NCBI Gene
HGNC ID
HGNC:12412
HGNC
Ensembl
ENSG00000137267
NCBI Gene
Aliases
CDCBM5, TUBB, TUBB2, dJ40E16.7
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13885Tubulin beta-2A chain4453Ensembl, GeneID, HGNC

Source UniProt

Patents42

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910301Q13885Espacenet
JP 2025517970 A2025-06-1210301Q13885Espacenet
US 11860162 B22024-01-021410Q13885Espacenet
JP 2023106701 A2023-08-0224Q13885Espacenet
US 11564998 B22023-01-315579Q13885Espacenet
US 11446398 B22022-09-2093577Q13885Espacenet
JP 2022092366 A2022-06-22591Q13885Espacenet
JP 2022524081 A2022-04-27196548Q13885Espacenet
US 11278629 B22022-03-2236Q13885Espacenet
US 11078247 B22021-08-0312151Q13885Espacenet

1 to 10 of 42

See all 42 patents

Drugs91

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ABT-751CHEMBL20684Tubulin beta inhibitorINHIBITORChEMBL
AGS-16C3FCHEMBL4594455Tubulin disrupting agentDISRUPTING AGENTChEMBL
ANETUMAB RAVTANSINECHEMBL2109629Tubulin inhibitorINHIBITORChEMBL
ANG1005CHEMBL1089636Tubulin inhibitorINHIBITORChEMBL
ANVATABART OPADOTINCHEMBL4297892Tubulin inhibitorINHIBITORChEMBL
APRUTUMAB IXADOTINCHEMBL4650293Tubulin inhibitorINHIBITORChEMBL
ASG-5MECHEMBL2109574Tubulin inhibitorINHIBITORChEMBL
AVE-9633CHEMBL2109266Tubulin inhibitorINHIBITORChEMBL
AZINTUXIZUMAB VEDOTINCHEMBL4297859Tubulin inhibitorINHIBITORChEMBL
BELANTAMAB MAFODOTINCHEMBL4298209Tubulin inhibitorINHIBITORChEMBL

1 to 10 of 91

See all 91 drugs

Trials8,740

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07604766PACLITAXELPHASE3ClinicalTrials.gov
NCT07602907PACLITAXELPHASE2ClinicalTrials.gov
NCT07601737PACLITAXELPHASE2ClinicalTrials.gov
NCT07601178PACLITAXELPHASE2ClinicalTrials.gov
NCT07599163PACLITAXELClinicalTrials.gov
NCT07595770PACLITAXELPHASE2ClinicalTrials.gov
NCT07594548PACLITAXELPHASE1ClinicalTrials.gov
NCT07591467DOCETAXELPHASE3ClinicalTrials.gov
NCT07589972VINORELBINEClinicalTrials.gov
NCT07588698VINCRISTINE SULFATEPHASE2ClinicalTrials.gov

1 to 10 of 8,740

See all 8,740 trials

NIH grants819

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTUBB2A papersNewest fiscal year
P30CA016672Cancer Center Support Grant52025
R01CA157823Genetic Susceptibility and Biomarkers of Platinum-related Toxicities32025
R01NS058721ACC: Callosal Agenesis as a Window into Common Neurodevelopmental Disorders32025
P30CA014599Cancer Center Support Grant22025
P30CA016086Cancer Center Support Grant22025
P30CA016087Cancer Center Support Grant22025
P30CA044579University of Virginia Cancer Center Support Grant22025
P30CA046934University of Colorado Cancer Center Support Grant22025
P30CA054174Mays Cancer Center at UT Health SA22025
P30ES017885Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD)22025

1 to 10 of 819Source NIH's project files

See all 819 nih grants

Papers1,014

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Comparative toxicoproteomics reveals distinct proteostasis and ribosomal stress signatures of CMIT and PHMG.Toxicol In Vitro202742702274PubTator, text miningPubMed
Developmental Profiles Associated with TUBA1A, TUBB2A, TUBB2B, and TUBB3 Tubulinopathy Conditions.Am J Intellect Dev Disabil202642593952PubTator, text miningPubMed
Genotypic and phenotypic heterogeneity in tubulinopathies: insights from a Turkish multicenter cohort.Neurol Sci202642472988PubTator, text miningPubMed
Immunometabolic reprogramming of Mycobacterium tuberculosis-responsive memory CD4+ T cell subsets is linked to long-term protective immunity.Front Tuberc202642368172PubTator, text miningPubMed
Genetic and Molecular Interconnections Between Chronic Obstructive Pulmonary Disease and Osteoporosis: Insights from Single-Cell and Mendelian Randomization Analyses.Int J Chron Obstruct Pulmon Dis202642180802PubTator, text miningPubMed
Investigating the Function of C‑Terminal Tails of Human Tubulin Isotypes in the Motility Regulation of Cytoplasmic Dynein.ACS Omega202642179625PubTator, text miningPubMed
Decoding Pathogenic Mutational Landscapes in Alzheimer's Disease Through Integrated Transcriptomics.Hum Mutat202642131724PubTator, text miningPubMed
Integrative single-cell and spatial multi-Omics analyses identify NETs-driven colon cancer subtypes with distinct metabolic features and prognostic implications.J Transl Med202642106773PubTator, text miningPubMed
A Novel TUBB2A Variant Causing Ataxia With Preserved Ambulation Into Adulthood.Am J Med Genet A202642050746PubTator, text miningPubMed
Novel Prognostic and Predictive miRNA Biomarkers Shape the Landscape of T Cell Dysfunction in Cancer.J Cell Mol Med202641923561PubTator, text miningPubMed

1 to 10 of 1,014

See all 1,014 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7280

GET https://conductscience.org/api/genes/v1/7280/patents?page=2