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Gene · 7284

TUFM: Tu translation elongation factor, mitochondrial

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TUFM: Tu translation elongation factor, mitochondrial. Genes, record 7284. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7284

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Gene

Symbol
TUFM
HGNC
Name
Tu translation elongation factor, mitochondrial
HGNC
NCBI Gene ID
7284
NCBI Gene
HGNC ID
HGNC:12420
HGNC
Ensembl
ENSG00000178952
NCBI Gene
Aliases
COXPD4, EF-TuMT, EFTU, EFTu, P43
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P49411Elongation factor Tu, mitochondrial4555Ensembl, GeneID, HGNC

Source UniProt

Patents18

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468485P49411Espacenet
EP 4650780 A22025-11-195433P49411Espacenet
JP 2025517970 A2025-06-125433P49411Espacenet
US 11446398 B22022-09-2093327P49411Espacenet
JP 2022524081 A2022-04-27196298P49411Espacenet
US 11078247 B22021-08-0312168P49411Espacenet
JP 2019054813 A2019-04-11248920P49411Espacenet
JP 2017121241 A2017-07-13248920P49411Espacenet
JP 2015516143 A2015-06-08248920P49411Espacenet
JP 2014524015 A2014-09-1845P49411Espacenet

1 to 10 of 18

See all 18 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,255

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTUFM papersNewest fiscal year
R01GM072528Molecular analysis of accurate ribosomal translocation72025
P30CA016086Cancer Center Support Grant42025
R01DK075787Biological Insights from Genetic Investigation of ANthropometric Traits (GIANT) Across the Allelic Spectrum42025
P01HL114501Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette Smokers32025
P30CA008748Cancer Center Support Grant32025
P30DK020541NYR-Diabetes Research Center (NYR-DRC)32025
R01DK062370Identifying Genes for Type 2 Diabetes: FUSION32025
R01DK093757Genetic epidemiology of rare and regulatory variants for metabolic traits32025
ZIASC007263Activating Cell Death Pathways in Breast Cancer Cells32025
P01CA092584Structural Cell Biology of DNA Repair Machines22025

1 to 10 of 1,255Source NIH's project files

See all 1,255 nih grants

Papers1,661

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Metagenomic Characterisation of Antibiotic Resistance in Anaerobic Digesters and Their Implications for Environmental Health.Environ Microbiol Rep202642817903PubTator, text miningPubMed
Potential therapeutic targets for obstructive sleep Apnea were identified through network pharmacology, WGCNA, machine learning, immune infiltration analysis, and ceRNA network.Integr Biol (Camb)202642537010PubTator, text miningPubMed
D81 Mutants Reveal Hidden EF-Tu Diversity while Natural Sequences Preserve Aspartate.Comput Struct Biotechnol J202642433270PubTator, text miningPubMed
Innovative epitope-based ELISA assay for detecting Group B Streptococcus carriage in pregnant women.Appl Microbiol Biotechnol202642265351PubTator, text miningPubMed
Evidence for the connectivity of antibiotic resistance genes between seamount and coastal environments.Ecotoxicol Environ Saf202642214309PubTator, text miningPubMed
Detection and characterization of protein methylation in bacteriophages and their host, Cellulophaga baltica, during infection.mSystems202642148748PubTator, text miningPubMed
TGM2-TUFM promotes acquired resistance to EGFR-TKIs in EGFR-mutated NSCLC through p62-mediated lipophagy.Respir Res202642106683PubTator, text miningPubMed
SPSB3-mediated K48- and K63- linked ubiquitination and degradation of TUFM promote apoptosis induced by myocardial ischemia/reperfusion injury.Cell Biol Toxicol202642082827PubTator, text miningPubMed
Japanese encephalitis virus degrades TRAF3 to suppress type I interferon and promote viral replication through NS5 and host TUFM proteins.Vet Res202641935318PubTator, text miningPubMed
Extracellular vesicle therapies in regenerative endodontic procedures: A systematic review and meta-analysis of in vivo studies.Sci Prog202641910440PubTator, text miningPubMed

1 to 10 of 1,661

See all 1,661 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7284

GET https://conductscience.org/api/genes/v1/7284/patents