Gene · 7284
TUFM: Tu translation elongation factor, mitochondrial
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TUFM: Tu translation elongation factor, mitochondrial. Genes, record 7284. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/7284
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P49411 | Elongation factor Tu, mitochondrial | 455 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents18
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 68485 | P49411 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 5433 | P49411 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 5433 | P49411 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 93327 | P49411 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 196298 | P49411 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 12168 | P49411 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 248920 | P49411 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 248920 | P49411 | Espacenet |
| JP 2015516143 A | 2015-06-08 | 248920 | P49411 | Espacenet |
| JP 2014524015 A | 2014-09-18 | 45 | P49411 | Espacenet |
1 to 10 of 18
See all 18 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,255
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TUFM papers | Newest fiscal year |
|---|---|---|---|
| R01GM072528 | Molecular analysis of accurate ribosomal translocation | 7 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 4 | 2025 |
| R01DK075787 | Biological Insights from Genetic Investigation of ANthropometric Traits (GIANT) Across the Allelic Spectrum | 4 | 2025 |
| P01HL114501 | Distinct and Overlapping Pathways of Fibrosis and Emphysema in Cigarette Smokers | 3 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30DK020541 | NYR-Diabetes Research Center (NYR-DRC) | 3 | 2025 |
| R01DK062370 | Identifying Genes for Type 2 Diabetes: FUSION | 3 | 2025 |
| R01DK093757 | Genetic epidemiology of rare and regulatory variants for metabolic traits | 3 | 2025 |
| ZIASC007263 | Activating Cell Death Pathways in Breast Cancer Cells | 3 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 2 | 2025 |
1 to 10 of 1,255Source NIH's project files
See all 1,255 nih grantsPapers1,661
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Metagenomic Characterisation of Antibiotic Resistance in Anaerobic Digesters and Their Implications for Environmental Health. | Environ Microbiol Rep | 2026 | 42817903 | PubTator, text mining | PubMed |
| Potential therapeutic targets for obstructive sleep Apnea were identified through network pharmacology, WGCNA, machine learning, immune infiltration analysis, and ceRNA network. | Integr Biol (Camb) | 2026 | 42537010 | PubTator, text mining | PubMed |
| D81 Mutants Reveal Hidden EF-Tu Diversity while Natural Sequences Preserve Aspartate. | Comput Struct Biotechnol J | 2026 | 42433270 | PubTator, text mining | PubMed |
| Innovative epitope-based ELISA assay for detecting Group B Streptococcus carriage in pregnant women. | Appl Microbiol Biotechnol | 2026 | 42265351 | PubTator, text mining | PubMed |
| Evidence for the connectivity of antibiotic resistance genes between seamount and coastal environments. | Ecotoxicol Environ Saf | 2026 | 42214309 | PubTator, text mining | PubMed |
| Detection and characterization of protein methylation in bacteriophages and their host, Cellulophaga baltica, during infection. | mSystems | 2026 | 42148748 | PubTator, text mining | PubMed |
| TGM2-TUFM promotes acquired resistance to EGFR-TKIs in EGFR-mutated NSCLC through p62-mediated lipophagy. | Respir Res | 2026 | 42106683 | PubTator, text mining | PubMed |
| SPSB3-mediated K48- and K63- linked ubiquitination and degradation of TUFM promote apoptosis induced by myocardial ischemia/reperfusion injury. | Cell Biol Toxicol | 2026 | 42082827 | PubTator, text mining | PubMed |
| Japanese encephalitis virus degrades TRAF3 to suppress type I interferon and promote viral replication through NS5 and host TUFM proteins. | Vet Res | 2026 | 41935318 | PubTator, text mining | PubMed |
| Extracellular vesicle therapies in regenerative endodontic procedures: A systematic review and meta-analysis of in vivo studies. | Sci Prog | 2026 | 41910440 | PubTator, text mining | PubMed |
1 to 10 of 1,661
See all 1,661 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/7284
GET https://conductscience.org/api/genes/v1/7284/patents