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Gene · 728655

HULC: hepatocellular carcinoma up-regulated long non-coding RNA

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. HULC: hepatocellular carcinoma up-regulated long non-coding RNA. Genes, record 728655. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/728655

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Gene

Symbol
HULC
HGNC
Name
hepatocellular carcinoma up-regulated long non-coding RNA
HGNC
NCBI Gene ID
728655
NCBI Gene
HGNC ID
HGNC:34232
HGNC
Ensembl
ENSG00000285219
NCBI Gene
Aliases
HCCAT1, LINC00078, NCRNA00078
NCBI Gene
Type
ncRNA
NCBI Gene

Proteins0

Reviewed human proteins whose Swiss-Prot entry states the gene.

None in this release.

Patents0

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

None in this release.

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants328

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleHULC papersNewest fiscal year
P30CA016672Cancer Center Support Grant82025
ZIAAG000511Post-transcriptional control of Proliferation, Stress Response & Carcinogenesis42025
ZIAAG000393Influence of Post-transcriptional Gene Regulation on Cell Senescence and Aging32025
I01BX000332Posttranscriptional Control of Gut Mucosal Defense and Homeostasis22025
P30CA008748Cancer Center Support Grant22025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant22025
P30CA023168Cancer Center Support Grant22025
P30CA196521The Tisch Cancer Institute - Cancer Center Support Grant22025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology22025
P50CA127001SPORE in Brain Cancer22025

1 to 10 of 328Source NIH's project files

See all 328 nih grants

Papers1,629

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Pro-inflammatory and autophagic pathways in lung cancer: dysregulation of key genes ADINR, C/EBPα, CHAST, ATG5, IL-1B, and DICER1-AS1.Biochem Biophys Rep202642741253PubTator, text miningPubMed
A One-Pot Reverse Transcriptase-Mediated, Pre-amplification-Free CRISPR/Cas12a Assay for Ultrasensitive Nucleic Acid Detection.ACS Sens202642603302PubTator, text miningPubMed
Circadian rhythm lncRNA NRON is dysregulated in autism spectrum disorder: an observational study.Biochem Biophys Rep202642434338PubTator, text miningPubMed
Decoding the functional landscape of long non-coding RNAs in hepatocellular carcinoma: molecular mechanisms, clinical implications, and therapeutic prospects.J Egypt Natl Canc Inst202642371299PubTator, text miningPubMed
Exosomal lncRNAs HOTAIR, HULC, and ANRIL: Decoding the Biomarker Landscape of Sporadic Triple-Negative Breast Cancer.Int J Mol Sci202642196289PubTator, text miningPubMed
Circulating Long Non-Coding RNAs as a Promising Non-Invasive Tool to Trace Adiposity Capacity Following Obesity Surgery.Life (Basel)202642195283PubTator, text miningPubMed
M6A-modified lncRNA HULC promotes osteosarcoma progression by stabilizing GLUT1 mRNA through interaction with TAF15.Cell Oncol (Dordr)202642184047PubTator, text miningPubMed
ShapeRNA: an integrated web server for RNA secondary structure, ensemble, and functional analysis.Nucleic Acids Res202642023506PubTator, text miningPubMed
The lncRNA-DNA Methylation Axis in Hepatocellular Carcinoma: Mechanisms, Epigenetic Plasticity, and Biological Implications.Biology (Basel)202641892218PubTator, text miningPubMed
Role of liver X receptors in the pathogenesis and treatment of chronic liver disease (Review).Mol Med Rep202641860051PubTator, text miningPubMed

1 to 10 of 1,629

See all 1,629 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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