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Gene · 7292

TNFSF4: TNF superfamily member 4

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. TNFSF4: TNF superfamily member 4. Genes, record 7292. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/7292

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
TNFSF4
HGNC
Name
TNF superfamily member 4
HGNC
NCBI Gene ID
7292
NCBI Gene
HGNC ID
HGNC:11934
HGNC
Ensembl
ENSG00000117586
NCBI Gene
Aliases
CD134L, CD252, GP34, OX-40L, OX4OL, TNLG2B, TXGP1, gp34
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P23510Tumor necrosis factor ligand superfamily member 41831Ensembl, GeneID, HGNC

Source UniProt

Patents546

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026213500 A12026-10-08739P23510Espacenet
WO 2026183237 A12026-09-03133P23510Espacenet
EP 4755917 A12026-06-1030P23510Espacenet
JP 2026089698 A2026-06-0156P23510Espacenet
JP 2026086743 A2026-05-26182P23510Espacenet
JP 2026077646 A2026-05-13102P23510Espacenet
JP 2026062687 A2026-04-10102P23510Espacenet
EP 4705273 A22026-03-11335P23510Espacenet
EP 4705347 A22026-03-11739P23510Espacenet
JP 2026028258 A2026-02-1923P23510Espacenet

1 to 10 of 546

See all 546 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AMLITELIMABCHEMBL4594569Tumor necrosis factor ligand superfamily member 4 inhibitorINHIBITORChEMBL
OXELUMABCHEMBL2108720Tumor necrosis factor ligand superfamily member 4 inhibitorINHIBITORChEMBL

Trials17

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT06557772AMLITELIMABPHASE2ClinicalTrials.gov
NCT06444451AMLITELIMABPHASE2ClinicalTrials.gov
NCT06407934AMLITELIMABPHASE3ClinicalTrials.gov
NCT06241118AMLITELIMABPHASE3ClinicalTrials.gov
NCT06224348AMLITELIMABPHASE3ClinicalTrials.gov
NCT06195072AMLITELIMABPHASE2ClinicalTrials.gov
NCT06181435AMLITELIMABPHASE3ClinicalTrials.gov
NCT06130566AMLITELIMABPHASE3ClinicalTrials.gov
NCT06118099AMLITELIMABPHASE2ClinicalTrials.gov
NCT06033833AMLITELIMABPHASE2ClinicalTrials.gov

1 to 10 of 17

See all 17 trials

NIH grants2,508

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA016672Cancer Center Support Grant232025
P30CA008748Cancer Center Support Grant192025
U19AI070535Airway Inflammation and Airway Remodeling in Severe Asthma142025
R01AI024717Genetic Linkage in Lupus122025
P30CA016359Cancer Center Support Grant92025
U54GM104938Oklahoma Shared Clinical and Translational Resources92025
P30CA016086Cancer Center Support Grant82025
P01CA065493Off-the-Shelf Immune Effector Cells for Hematological Malignancies62025
U19AI104209Integrated Genomic and Functional Studies of Immunotherapy for Multi-Food Allergy62025
UL1TR001863Yale Clinical and Translational Science Award62025

1 to 10 of 2,508Source NIH's project files

See all 2,508 nih grants

Papers4,164

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823603PubTator, text miningPubMed
42787635PubTator, text miningPubMed
42761973PubTator, text miningPubMed
42752301PubTator, text miningPubMed
42731877PubTator, text miningPubMed
42667317PubTator, text miningPubMed
42653386PubTator, text miningPubMed
42638514PubTator, text miningPubMed
42627772PubTator, text miningPubMed
42564165PubTator, text miningPubMed

1 to 10 of 4,164

See all 4,164 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/7292

GET https://conductscience.org/api/genes/v1/7292/patents?page=2